International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

The in vitro antioxidant and alphaglucosidase inhibitory activity of extracts from Zingiber zerumbet Linn rhizomes

Trinh Ngoc Thao Vy, Lam Vinh Nien

Department of Medicine and Pharmacy, Tay Nguyen University, Buon Ma Thuot, Dak Lak 630000, Vietnam; University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 70000, Vietnam

Article Information

Volume / Issue6 / 2 (2025)
Pages50-52
AccessOpen Access

Publication Timeline

  • Received03 March 2025
  • Accepted05 April 2025

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Abstract

The total methanol residue, n-hexane and chloroform extracts from Zingiber zerumbet Linn rhizomes have been evaluated for α-glucosidase inhibitory activity in an attempt to identify potential active ingredients in natural products. The results showed that the chloroform extract inhibited α-glucosidase more effectively than the positive control acarbose, with an IC50 value of 127.8 µg/mL. This antioxidant activity of the crude extract; fractional extracts including: n-hexane extract, chloroform extract, and methanol extract of from Zingiber zerumbet has been investigated using DPPH assay. The results showed that the crude chloroform extract exhibited good antioxidant activities with IC50 value of 2.09 µg/mL.

Keywords

Zingiber zerumbetchloroform extractα-glucosidaseantioxidant

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How to Cite

Vy, T. N. T., & Nien, L. V. (2025). The in vitro antioxidant and alphaglucosidase inhibitory activity of extracts from Zingiber zerumbet Linn rhizomes. International Journal of Medical and All Body Health Research, 6(2), 50-52. https://doi.org/10.54660/IJMBHR.2025.6.2.50-52

Vy, Trinh Ngoc Thao, and Lam Vinh Nien. "The in vitro antioxidant and alphaglucosidase inhibitory activity of extracts from Zingiber zerumbet Linn rhizomes." International Journal of Medical and All Body Health Research, vol. 6, no. 2, 2025, pp. 50-52. https://doi.org/10.54660/IJMBHR.2025.6.2.50-52.

Vy, T. N. T. and Nien, L. V. (2025) 'The in vitro antioxidant and alphaglucosidase inhibitory activity of extracts from Zingiber zerumbet Linn rhizomes', International Journal of Medical and All Body Health Research, 6(2), pp. 50-52. doi: 10.54660/IJMBHR.2025.6.2.50-52.

Vy TNT, Nien LV. The in vitro antioxidant and alphaglucosidase inhibitory activity of extracts from Zingiber zerumbet Linn rhizomes. International Journal of Medical and All Body Health Research. 2025;6(2):50-52. doi:10.54660/IJMBHR.2025.6.2.50-52

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