International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Is Covid-19 severe in patients with Alzheimer's disease?

Mohaddeseh Mirzaei

MSc in Geriatric Nursing, University of Social Welfare and Rehabilitation Sciences (USWR), Tehran, Iran

Article Information

Volume / Issue4 / 2 (April-June 2023)
Pages53-56
AccessOpen Access

Publication Timeline

  • Received22 May 2023
  • Accepted10 June 2023

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Abstract

Alzheimer's disease (AD), as a degenerative neurodegenerative disease that has a growing trend causes the exacerbation of the infectious disease of COVID-19, or on the contrary, the infection of Covid-19 can aggravate the symptoms of AD and the severe form of COVID-19 appears. There are several mechanisms for the worsening of AD condition after COVID-19. It is reasonable to assume that COVID-19 has a more severe impact on patients with comorbidities, including those with AD. As such, individuals with AD should take additional preventive measures to avoid contracting COVID-19, as they are at a heightened risk of developing severe symptoms of the disease, which could result in increased mortality rates.

 

Keywords

Alzheimer's diseaseCOVID-19SARS-CoV-2Infection

References

  1. Mehta RI, Schneider JA. What is ‘Alzheimer's disease’? The neuropathological heterogeneity of clinically defined Alzheimer's dementia. Current opinion in neurology. 2021; 34(2):237-45. [Google Scholar][Crossref]
  2. Armstrong RA. What causes Alzheimer’s disease?. Folia Neuropathologica. 2013; 51(3):169-88. [Google Scholar][Crossref]
  3. Lyketsos CG, Carrillo MC, Ryan JM, Khachaturian AS, Trzepacz P, Amatniek J, Cedarbaum J, Brashear R, Miller DS. Neuropsychiatric symptoms in Alzheimer’s disease. Alzheimer's & Dementia. 2011; 7(5):532-9. [Google Scholar][Crossref]
  4. Rosenberg PB, Nowrangi MA, Lyketsos CG. Neuropsychiatric symptoms in Alzheimer's disease: What might be associated brain circuits?. Molecular aspects of medicine. 2015; 43:25-37. [Google Scholar][Crossref]
  5. Li X, Feng X, Sun X, Hou N, Han F, Liu Y. Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2019. Frontiers in Aging Neuroscience. 2022; 14:937486. [Google Scholar][Crossref]
  6. Zhang E. Alzheimer's Disease: Why is Early Detection Important?. Journal of Student Research, 2023, 12(2). [Google Scholar][Crossref]
  7. Zeisel J. Environmental design effects on Alzheimer symptoms in long-term care residences. World hospitals and health services: the official journal of the International Hospital Federation. 2000; 36(3):27-31. [Google Scholar][Crossref]
  8. Tabatabaii SA, Soltani P, Khanbabaee G, Sharma D, Valizadeh R, Farahbakhsh N, Tariverdi M, Pourghasem M, Tabiei E. SARS Coronavirus 2, severe acute respiratory syndrome, and middle east respiratory syndrome in children: A review on epidemiology, clinical presentation, and diagnosis. Archives of Pediatric Infectious Diseases. 2020; 8(4):1-8. [Google Scholar][Crossref]
  9. Mirshamsi M, Ghiasi N, Heidari S, Hosseinpour P, Hassanlouei B, Hashemipour SM, Aidenloo NS, Valizadeh R. Conjunctivitis and other ocular manifestation following Covid-19; updated information about transmission of Covid-19 by eye. Immunopathologia Persa. 2021; 7(2):e28. [Google Scholar][Crossref]
  10. Dadashzadeh N, Farshid S, Valizadeh R, Nanbakhsh M, Rahimi MM. Acute respiratory distress syndrome in COVID-19. Immunopathologia Persa. 2020; 6(2):e16. [Google Scholar][Crossref]
  11. Besharat S, Alamda NM, Dadashzadeh N, Talaie R, Mousavi SS, Barzegar A, Tavana S, Valizadeh R, Frouzesh M. Clinical and demographic characteristics of patients with COVID-19 who died in Modarres hospital. Open Access Macedonian Journal of Medical Sciences. 2020; 8(T1):144-9. [Google Scholar][Crossref]
  12. Mohamad Rahimi M, Jahantabi E, Lotfi B, Forouzesh M, Valizadeh R, Farshid S. Renal and liver injury following the treatment of COVID-19 by remdesivir. Journal of Nephropathology. 2021; 10(2):1-4. [Google Scholar][Crossref]
  13. Ciaccio M, Lo Sasso B, Scazzone C, Gambino CM, Ciaccio AM, Bivona G, Piccoli T, Giglio RV, Agnello L. COVID-19 and Alzheimer’s disease. Brain sciences. 2021; 11(3):305. [Google Scholar][Crossref]
  14. de Erausquin GA, Snyder H, Carrillo M, Hosseini AA, Brugha TS, Seshadri S, CNS SARS‐CoV‐2 Consortium. The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning. Alzheimer's & Dementia. 2021; 17(6):1056-65. [Google Scholar][Crossref]
  15. Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, Brayne C, Burns A, Cohen-Mansfield J, Cooper C, Costafreda SG. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet. 2020; 396(10248):413-46. [Google Scholar][Crossref]
  16. Bianchetti A, Rozzini R, Guerini F, Boffelli S, Ranieri P, Minelli G, Bianchetti L, Trabucchi M. Clinical presentation of COVID19 in dementia patients. The journal of nutrition, health & aging. 2020; 24:560-2. [Google Scholar][Crossref]
  17. Mohammadkhanizadeh A, Karimzadeh F. COVID-19 and Alzheimer's Disease: A Review of Mechanisms and Pathophysiology. Shefaye Khatam 2021; 9(2):151-159. [Google Scholar][Crossref]
  18. Smith JA, Das A, Ray SK, Banik NL. Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases. Brain research bulletin. 2012; 87(1): 10-20. [Google Scholar][Crossref]
  19. CarePort Health. Covid-19 report. https://careporthealth.com/wp-content/uploads/2020/05/COVID-19-Report-3.pdf. Date accessed: July 10, 2020. [Google Scholar][Crossref]
  20. D'Adamo H, Yoshikawa T, Ouslander JG. Coronavirus disease 2019 in geriatrics and long‐term care: the International Journal of Medical and All Body Health Research www.allmedicaljournal.com ABCDs of Covid‐19. Journal of the American Geriatrics Society. 2020; 68(5):912-7. [Google Scholar][Crossref]

How to Cite

Mirzaei, M. (2023). Is Covid-19 severe in patients with Alzheimer's disease?. International Journal of Medical and All Body Health Research, 4(2), 53-56.

Mirzaei, Mohaddeseh. "Is Covid-19 severe in patients with Alzheimer's disease?." International Journal of Medical and All Body Health Research, vol. 4, no. 2, 2023, pp. 53-56.

Mirzaei, M. (2023) 'Is Covid-19 severe in patients with Alzheimer's disease?', International Journal of Medical and All Body Health Research, 4(2), pp. 53-56.

Mirzaei M. Is Covid-19 severe in patients with Alzheimer's disease?. International Journal of Medical and All Body Health Research. 2023;4(2):53-56.

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