Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Co-Infections among Patients attending General Hospital, Wukari, Taraba State, North East, Nigeria
Article Information
Publication Timeline
- Received16 May 2023
- Accepted02 June 2023
Abstract
Human Immunodeficiency virus (HIV), Hepatitis B virus (HBV), and Hepatitis C virus (HCV) are all potent viral pathogens of public health significance. However, there is limited data regarding co-infection of HIV, HBV, and HCV in developing countries, especially Nigeria. Hence this study was carried out to determine the prevalence of HBV, HCV and HIV co-infections among patients in Wukari, Taraba State. One hundred (100) blood samples of patients attending Hospital in Wukari, Taraba state were collected and screened for Hepatitis B surface antigen, anti – HCV antigen and HIV antigen were included in this study. The venous blood samples were collected and screened for Hepatitis-B surface antigen (HBsAg), Anti-HCV antibodies and HIV antibodies using HBV Combo Rapid Test Cassette; TELL Rapid diagnostic strip as well as Determine and StakPat test strips using standard serological techniques. The results indicates prevalence rate of HBV was 15.0%, 20.0% males and 13.8% females, HCV was 5.0, with 3.3% males and with 6.2% females and HIV was 8%, 10.0% males and 7.1% females. The prevalence rates of HBV/HIV, HCV/HIV and HBV/HCV/HIV co-infections were 7.0%, 3.0% and 2.0% respectively. The prevalence of HBV/HCV/HIV and HBV/HCV/HIV infection was more among subjects within age range of 21-30 years (11.5%, 3.8% and 3.8%) and lowest within the age range of 11-20 years (4.5%, 0% and 0%). This study further reaffirms the need for routine baseline screening for this serological marker, as it is a major consideration in the initiation and choice of highly active Anti-Retroviral Therapy. Hence, the results obtained from this researched implies that patients should be encouraged to go for screening and know their status for proper management to avoid cirrhosis and liver cancer and take steps to avoid infecting other individuals. Also, for those that are seropositive, early diagnosis, treatment and vaccination are the recommended preventive measures. There is need for vigorous awareness campaigns on the routes of transmission of these infections and to educate people living in developing regions as to the deadly effect of these infections.
Keywords
Co-infectionHepatitis B VirusHepatitis C VirusHuman Immunodeficiency VirusPatientsGeneral HospitalWukariReferences
- Alo MN, Alhassan HM, Saidu AY, Ugah UI, Umar FA. Cd4 T cell count in patients concomitantly infected with HIV and Hepatitis B Virus in Sokoto State, Nigeria. World J Medical Sciences. 2013; 8(3):296-299. [Google Scholar][Crossref]
- Bello RH, Olabode HOK. Human immunodeficiency virus (HIV) and hepatitis B virus (HBV) co-infection amongst patients in Biu, Borno state- Nigeria. International Research Journal of Microbiology. 2013; 2:507-509. [Google Scholar][Crossref]
- Balogun TM, Emmanuel S, Ojerinde EF, et al. HIV, Hepatitis B and C viruses' coinfection among patients in a Nigerian tertiary hospital. Pan Afr Med J. 2012; 12:100. [Google Scholar][Crossref]
- Centers for Disease Control and Prevention. HIV and Men. U.S. Department of Health & Human Services. Archived from the original on December 1, 2019. Retrieved November 3, 2019. [Google Scholar][Crossref]
- Centers for Disease Control and Prevention. Q&A forHealth Professionals. Viral Hepatitis. Retrieved 28 September, 2020. [Google Scholar][Crossref]
- Edia-Asuke Z Abubakar, S Asuke. Seroprevalence of Hepatitis B infection among outpatients attending a public tertiary hospital in Kaduna state, Nigeria Trop. Med. Surg. 2015; 3(3):189. [Google Scholar][Crossref]
- Folade-Nwulia O, Searbery EC, Rinaldo CR, Badri S, Witt M, Thio CL. Comparative risk of liver-related mortalityfrom chronic HBV verses Chronic HCV infection. Clin Infect Dis. 2012; 55:507-13. [Google Scholar][Crossref]
- Imarenezor Edobor Peter Kenneth, Onolunosen Abel Abhadionmhen, Sunday Danya, Joyce Briska, Paula Paul Shinggu. Sero-prevalence of Hepatitis B virus and plasmodium co-infection profile among patients in Wukari and Environs, North East Nigeria. International Journal of Science and Research Archive. 2021; 03(01):114–123. [Google Scholar][Crossref]
- Imarenezor Edobor Peter Kenneth. Incidence of Malaria Parasite in Pregnant and Non Pregnant Women in Ewohimi, Edo State, Nigeria. American Journal of Microbiology and Biotechnology. 2017; 4(6):97-99. [Google Scholar][Crossref]
- Imarenezor EPK, Brown STC, Yakubu OE, Soken DC. Survey of Hepatitis B and C among students of Federal International Journal of Medical and All Body Health Research www.allmedicaljournal.com University Wukari, Taraba State, Nigeria. International Research Journal of Medicine and Medical Sciences. 2016; 4(3): 31-37. [Google Scholar][Crossref]
- Mohammadi M, Talei G, Sheikhian A. Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients. Virol J. 2010; 6:202. [Google Scholar][Crossref]
- Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiologyof hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology. 2013; 57(4):1333-42. [Google Scholar][Crossref]
- Nwolisa E, Mbanefo F, Ezeogu J, Amadi P. Prevalence of hepatitis B co-infection among HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria. Pan African Medical Journal. 2013; 14:89-97. [Google Scholar][Crossref]
- Odjimogho S, Agofure O, Oghenenioborue RA, Okandeji-Barry. Prevalence of Hepatitis B and C among HIV/AIDS patients attending Bingham University Teaching Hospital Jos, Plateau State Nigeria: A retrospective study. Journal of public health and Epidemiology. 2018; 10(6):198-204. [Google Scholar][Crossref]
- Ojide CK, Kalu EI, Ogbaini-Emevon E, Nwadike VU. Co-infections of hepatitis B and C with human immunodeficiency virus among adult patients attending human immunodeficiency virus outpatients clinic in Benin City, Nigeria. Niger J Clin Pract. 2015; 18:516-21. [Google Scholar][Crossref]
- Okoroiwu UH, Okafor MI, Asemota AE, kpokam CD. Seroprevalence of Transfusion Transmissible Infections (HBV, HCV, Syphilis and HIV) among prospective blood donors in Tertiary Health Care Facility in Calabar, Nigeria: An Eleven years evaluation: Bio-Med Central Journal of Public Health. 2018; 18:645-649. [Google Scholar][Crossref]
- Otegbayo JA, Taiwo BO, Akingbola TS, Odaibo GN, Adedapo KS, Penugonda S. Prevalence of hepatitis B and C seropositivityin a Nigerian cohort of HIV-infected patients. Ann Hepatol. 2010; 7:152-6. [Google Scholar][Crossref]
- Weitzel T, Rodríguez F, Noriega LM, Marcotti A, Duran L, Palavecino C. Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: A cross-sectional serosurvey. Procedure Library of Science One. 2020; 15(1):325-334. [Google Scholar][Crossref]
- World Health Organization. WHO | HIV and hepatitis coinfections. WHO, 2014. Archived from the original on April 18, 2014. Retrieved 2020-08-03. [Google Scholar][Crossref]
- World Health Organization. WHO validates elimination of mother-to-child transmission of HIV and syphilis in Cuba, 2015. Archived from the original on September 4, 2015. Retrieved August 30, 2015. [Google Scholar][Crossref]
- World Health Organization. World Health Organization, 2016. Global health sector strategy on viral hepatitis 2016-2021. Available from: https://www.who.int/hepatitis/ strategy2016-2021/ghss-hep/en/. Accessed April 23, 2021. [Google Scholar][Crossref]
- World Health Organization Global Hepatitis Report, 2017, p.33.[pdf] [Google Scholar][Crossref]
- World Health Organization. WHO: HIV and hepatitis coinfections. WHO, 2020. Archived from the original on April 1, 2014. Retrieved 31 July 2020. [Google Scholar][Crossref]
- World Health Organization. Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021. Www.who.int. Retrieved 2022-01-19. [Google Scholar][Crossref]
How to Cite
Kenneth, I. E. P., Vivian, A. I., Onolunosen, A. A., Nneoma, N. M., & Promise, E. A. (2023). Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Co-Infections among Patients attending General Hospital, Wukari, Taraba State, North East, Nigeria. International Journal of Medical and All Body Health Research, 4(2), 36-42.
Kenneth, Imarenezor Edobor Peter, et al. "Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Co-Infections among Patients attending General Hospital, Wukari, Taraba State, North East, Nigeria." International Journal of Medical and All Body Health Research, vol. 4, no. 2, 2023, pp. 36-42.
Kenneth, I. E. P., Vivian, A. I., Onolunosen, A. A., Nneoma, N. M. and Promise, E. A. (2023) 'Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Co-Infections among Patients attending General Hospital, Wukari, Taraba State, North East, Nigeria', International Journal of Medical and All Body Health Research, 4(2), pp. 36-42.
Kenneth IEP, Vivian AI, Onolunosen AA, Nneoma NM, Promise EA. Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) Co-Infections among Patients attending General Hospital, Wukari, Taraba State, North East, Nigeria. International Journal of Medical and All Body Health Research. 2023;4(2):36-42.
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