International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Biochemistry Research on Endemic and Regionally Unique Asian Plants for Anti Ageing: Challenges, Opportunities, and a Translational Roadmap

Elgi Zulfakar Diniy, Poncojari Wahyono, Abdulkadir Rahardjanto

Master of Biology Education, Postgraduate Program, Universitas Muhammadiyah Malang, Indonesia

Article Information

Volume / Issue5 / 4 (October-December 2024)
Pages256-260
AccessOpen Access

Publication Timeline

  • Received02 November 2024
  • Accepted04 December 2024

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Abstract

Asia contains exceptional botanical diversity and long-established traditions of medicinal plant use. This creates substantial opportunities for biochemistry research on endemic and regionally unique plants as sources of anti ageing actives for skin and healthy ageing applications. Anti ageing research, however, requires more than antioxidant screening: credible pathways must connect plant chemistry to mechanisms of ageing biology (oxidative stress, inflammation, extracellular matrix degradation, glycation, barrier dysfunction, and cellular senescence), followed by standardization, safety evaluation, and human evidence. This article provides a framework synthesis (≤2024) of endemic/regionally unique Asian plant biochemistry research for anti ageing, focusing on the coupled challenges and opportunities that determine scientific credibility and translation readiness. We integrate literature on skin ageing mechanisms and biomarkers (Fisher et al., 2002; Rittié & Fisher, 2015; Kammeyer & Luiten, 2015), natural products and bioactive polyphenols (Atanasov et al., 2021; Newman & Cragg, 2020), metabolomics standards and annotation bottlenecks (Fiehn, 2002; Sumner et al., 2007; Wolfender et al., 2019), and governance considerations under the Nagoya Protocol (CBD, 2011; Oberthür & Rosendal, 2014). Results are presented as two conceptual figures (a biochemical mechanism map and an evidence–translation matrix) and three implementation tables mapping biochemical targets, assay and evidence ladders, and institutional strategies for higher education. We argue that the most impactful university programs pair rigorous taxonomy and metadata with multi-omics chemical profiling, mechanism-linked assays (e.g., MMP inhibition, anti-glycation, senescence modulation), reproducible standardization, and staged human studies, while ensuring ethical access and benefit-sharing for local communities. The synthesis concludes with a practical roadmap to move endemic plant leads from discovery to responsible anti ageing innovation in Asia.

Keywords

Anti AgeingSkin AgeingEndemic PlantsAsiaPlant BiochemistryMetabolomicsNatural ProductsPolyphenolsMmp InhibitionAnti GlycationInflammationSenescenceTranslationStandardizationNagoya Protocol

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How to Cite

Diniy, E. Z., Wahyono, P., & Rahardjanto, A. (2024). Biochemistry Research on Endemic and Regionally Unique Asian Plants for Anti Ageing: Challenges, Opportunities, and a Translational Roadmap. International Journal of Medical and All Body Health Research, 5(4), 256-260. https://doi.org/10.54660/IJMBHR.2024.5.4.256-260

Diniy, Elgi Zulfakar, et al. "Biochemistry Research on Endemic and Regionally Unique Asian Plants for Anti Ageing: Challenges, Opportunities, and a Translational Roadmap." International Journal of Medical and All Body Health Research, vol. 5, no. 4, 2024, pp. 256-260. https://doi.org/10.54660/IJMBHR.2024.5.4.256-260.

Diniy, E. Z., Wahyono, P. and Rahardjanto, A. (2024) 'Biochemistry Research on Endemic and Regionally Unique Asian Plants for Anti Ageing: Challenges, Opportunities, and a Translational Roadmap', International Journal of Medical and All Body Health Research, 5(4), pp. 256-260. doi: 10.54660/IJMBHR.2024.5.4.256-260.

Diniy EZ, Wahyono P, Rahardjanto A. Biochemistry Research on Endemic and Regionally Unique Asian Plants for Anti Ageing: Challenges, Opportunities, and a Translational Roadmap. International Journal of Medical and All Body Health Research. 2024;5(4):256-260. doi:10.54660/IJMBHR.2024.5.4.256-260

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