International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Antibiotic Resistance Profile of Escherichia coli From Commercially-Marketed Kunun-zaki in Lafia Metropolis, Nasarawa State, Nigeria

Oloruntoba Anuoluwa Ibironke, Ehinmidu O Joseph, Moses Adondua Abah, Tolulope Iorwuese Ade, Faith Beyaan Auta, Ugba Mhii, Oluwayemisi Olufunke Fagboro, Giuseppina Edem Asuquo

Depatment of Microbiology, Faculty of Natural and Applied Sciences, University of Ilorin, Ilorin, Kwara State, Nigeria Depatrment of Pharmaceutics, Faculty of Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria; Depatrment of Pharmaceutics, Faculty of Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Kaduna State, Nigeria; Department of Biochemistry, Faculty of Pure and Applied Sciences, Federal University Wukari, Taraba State, Nigeria; Department of Microbiology, Faculty of Pure and Applied Sciences, Federal University Wukari, Taraba State, Nigeria; Depatment of Microbiology, Faculty of Pure and Applied Sciences, Joseph Sarwuan Tarkaa University, Benue State, Nigeria; Depatment of Microbiology, Faculty of Natural and Applied Sciences, University of Ilorin, Ilorin, Kwara State, Nigeria; Depatment of Microbiology, Faculty of Natural and Applied Sciences, Obong University, Obong Ntak, Akwa Ibom State, Nigeria

Article Information

Volume / Issue4 / 1 (January-March 2023)
Pages31-34
AccessOpen Access

Publication Timeline

  • Received17 February 2023
  • Accepted05 March 2023

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Abstract

Microbial contamination of locally-made beverages is a significant challenge as these beverages can serve as sources for the transmission of potential pathogens. Hence, this study was carried out to determine the prevalence and antibiotic resistance profile of Escherichia coli in commercially-marketed kunun-zaki in Lafia, Nasarawa State, Nigeria. Forty (40) kunun-zaki samples were collected from ten (10) different locations and cultured aerobically using standard microbiological techniques. Antibiotic sensitivity testing was carried out using the modified Kirby-Bauer disc diffusion method while the iodometric method was used for the detection of βlactamase production. A total of 13 (32.5%) E. coli isolates were recovered from the cultured kunun-zaki. Although all the isolates were susceptible to augmentin, the isolates were resistant to trimethoprim-sulfamethoxazole (23.08%), chloramphenicol, amoxicillin, ofloxacin, and streptomycin (15.38% each), and sparfloxacin, ciprofloxacin, gentamicin, and pefloxacin (7.69% each). Analysis of the resistance profile of E. coli isolates showed that 5 (38.46%) were sensitive to all antibiotics, 5 (38.46%) were resistant to one antibiotic, 2 (15.38%) were resistant to 3 antibiotics, and 1(7.70%) was resistant to four antibiotics. Also, only 2 (15.38%) isolates were positive for β lactamase production. High prevalence of Escherichia coli in commercially-marketed kunun-zaki is a significant public health concern as this drink is directly ingested after purchase. Hence, producers of this beverage should be properly sensitized on hygienic ways to prevent microbial contamination during the production of kunun-zaki.

 

Keywords

Microbial contaminationEscherichia colikunun-zakibeveragesAntibiotic resistance

References

  1. Ezeonu CS, Tatah SV, Imo C, Yakubu OE, Garba QH, Arowora K, Umaru IJ, Abah MA, Abu MS, Yohanna ER, Timothy M. Antioxidant potential of ginger extract on metals (lead, cadmium, and boron) induced oxidative stress in maize plant. Asian Journal of Tropical Biotechnology. 2022; 19:45-51. [Google Scholar][Crossref]
  2. Amusa NA, and Odunbaku OA. Microbiological and nutritional quality of hawked kunun (A sorghum based non-alcoholic beverage) widely consumed in Nigeria. Pakistan Journal of Nutrition. 2009; 8(1):20-25. [Google Scholar][Crossref]
  3. Makut MD, Nyam MA, Obeikezie SO,and Abubakar AE. Antibiogram of bacteria isolated from kununzaki drink sold in Keffi metropolis. American Journal of Infectious Diseases. 2013; 9(3):71-76. [Google Scholar][Crossref]
  4. Atata RF, Ibrahim YKE, Giwa A, and Akanbi AA. Antibiotics resistance pro file of bacterial isolates from surgical site and hospital environment in aUniversity Teaching Hospital in Nigeria. Journal of Medicine and Medical Sciences. 2013; 4(4):181-187. [Google Scholar][Crossref]
  5. Umaru GA, Tukur IS, Akensire UA, Adamu Z, Bello OA, Shawulu HBA, Audu M, Sunkani JB, Adamu GS, Adamu NB. Microflora ofkunun-zakiand sobo drinks in relation to public health in Jalingo metropolis,North Eastern Nigeria. International Journal of Food Research. 2014; 1:16-21. [Google Scholar][Crossref]
  6. Elmahmood AM, and Doughari JH. Microbiological quality assessment of kununzakibeverage sold in Girei town of Adamawa state, Nigeria. African Journal of Food Science. 2007; 1:11-15. [Google Scholar][Crossref]
  7. Zhema PA, Abah MA, Emochone RY, Okoli EC, Saaku SA, Habibu B. Investigation of trace metal contamination in bread baked andsold in Wukari. Global Science Journal. 2022; 10(2):2076-2084. [Google Scholar][Crossref]
  8. Cheesebrough M.Medical Laboratory Manual for Tropical Countries. Cambridge: Cambridge University Press, 2006, Pp. 49-97. [Google Scholar][Crossref]
  9. Clinical and Laboratory Standards Institute (CLSI). M100: Performance Standards for Antimicrobial Susceptibility Testing (32 nd Edn). © Clinical and Laboratory StandardsInstitute, 2022; 362p. [Google Scholar][Crossref]
  10. Bidya S, Suman RS. Comparative study of three β lactamase test methods in Staphylococcus aureus isolated from two Nepalese hospitals. Open Journal of Clinical Diagnostics. 2014; 4:47-52. [Google Scholar][Crossref]
  11. Wilke MS, Lovering AL. Strynadka CJN. Beta-lactam antibiotic resistance: A current structural perspective. Current opinion in Microbiology. 2005; 8(5):525-533. [Google Scholar][Crossref]
  12. Andrews J. Detection of extended spectrum Beta-lactamases (ESBLs) in E.coli and Klebsiella species. British society for antimicrobial chemotherapy BSAC, 2009, Pp. 674. [Google Scholar][Crossref]
  13. Kok FK, Lisa S, Kalai M. Beta-lactam antibiotics: From antibiotics to resistance and bacteriology. 2010; 118(1):1-36. [Google Scholar][Crossref]

How to Cite

Ibironke, O. A., Joseph, E. O., Abah, M. A., Ade, T. I., Auta, F. B., Mhii, U., Fagboro, O. O., & Asuquo, G. E. (2023). Antibiotic Resistance Profile of Escherichia coli From Commercially-Marketed Kunun-zaki in Lafia Metropolis, Nasarawa State, Nigeria. International Journal of Medical and All Body Health Research, 4(1), 31-34.

Ibironke, Oloruntoba Anuoluwa, et al. "Antibiotic Resistance Profile of Escherichia coli From Commercially-Marketed Kunun-zaki in Lafia Metropolis, Nasarawa State, Nigeria." International Journal of Medical and All Body Health Research, vol. 4, no. 1, 2023, pp. 31-34.

Ibironke, O. A., Joseph, E. O., Abah, M. A., Ade, T. I., Auta, F. B., Mhii, U., Fagboro, O. O. and Asuquo, G. E. (2023) 'Antibiotic Resistance Profile of Escherichia coli From Commercially-Marketed Kunun-zaki in Lafia Metropolis, Nasarawa State, Nigeria', International Journal of Medical and All Body Health Research, 4(1), pp. 31-34.

Ibironke OA, Joseph EO, Abah MA, Ade TI, Auta FB, Mhii U, et al. Antibiotic Resistance Profile of Escherichia coli From Commercially-Marketed Kunun-zaki in Lafia Metropolis, Nasarawa State, Nigeria. International Journal of Medical and All Body Health Research. 2023;4(1):31-34.

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