International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Use of Chlorhexidine gluconate in wound healing and its potential formation of granulation tissue

Juan Camilo Gelvez Cáceres, Ana María Garcés Pérez, Silvia Juliana Serrano Baez, César Augusto Arroyo Pérez, María Carolina Causil Galvis, María del Mar Muñoz, Estefanía Rey Paez, Alberto Buenrostro Emporo

Article Information

Volume / Issue2 / 4 (October-December 2021)
Pages20-23
AccessOpen Access

Publication Timeline

  • Received03 September 2021
  • Accepted18 September 2021

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Abstract

Background: According to the literature described, antiseptics are chemical agents whose function is to inhibit or destroy the growth of microorganisms in living tissues, among the most widely used antiseptics is chlorhexidine gluconate, which is widely used in hospitals due to its characteristics and properties. different applications, which make a powerful agent to prevent infection at the wound site.rnMethodology: A narrative review was carried out in which databases such as pubmed, science direct, scielo, academic Google, among others, were used to search for articles, these were taken from indexed journals in first and second languages. As keywords, the descriptors DECS and MeSH, antiseptics, chlorhexidine gluconate, wounds, infection were used.rnResults: Several studies have demonstrated the effectiveness of chlorhexidine gluconate, in preventing infections in wounds, and various application techniques have been used, such as compresses impregnated with the antiseptic, washing in the preoperative site before the incision, showers or baths, among others. All demonstrating the high efficiency in reducing bacterial colonies.

Keywords

Chlorhexidine gluconateantisepticswoundsinfection

References

  1. Saavedra Lozano J, Terrón Cuadrado M. Antisépticos. Guía_ABE. Infecciones en Pediatría. Guía rápida para la selección del tratamiento antimicrobiano empírico [en línea] [actualizado el 21/11/2007; consultado el dd/mm/aaaa], 2007. Disponible en http://www.guiaabe.es [Google Scholar][Crossref]
  2. Edmiston CE, Bruden B, Rucinski MC, Henen C, Graham MB, Lewis BL. Reducing the risk of surgical site infections: Does chlorhexidine gluconate provide a risk reduction benefit? American Journal of Infection Control mayo de. 2013; 41(5):S49-55. [Google Scholar][Crossref]
  3. Maya JJ, Ruiz SJ, Pacheco R, Valderrama SL, Villegas MV. Papel de la clorhexidina en la prevención de las infecciones asociadas a la atención en salud. Infectio. junio de. 2011; 15(2):98-107. [Google Scholar][Crossref]
  4. Bose KS, Sarma RH. Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution. Biochem Biophys Res Commun. 27 de octubre de. 1975; 66(4):1173-9. [Google Scholar][Crossref]
  5. González LL, Isabel Gutiérrez Pérez M, Eulalia Lucio-Villegas Menéndez M, Lluch NA, Luisa Morató Agustí M, Cachafeiro SP. Introducción a los antisépticos. Atención Primaria. mayo de. 2014; 46:1-9. [Google Scholar][Crossref]
  6. Rhee Y, Palmer LJ, Okamoto K, Gemunden S, International Journal of Medical and all body Health Research www.allmedicaljournal.com 23 Hammouda K, Kemble SK, et al. Differential Effects of Chlorhexidine Skin Cleansing Methods on Residual Chlorhexidine Skin Concentrations and Bacterial Recovery. Infect Control Hosp Epidemiol. abril de. 2018; 39(4):405-11. [Google Scholar][Crossref]
  7. Chicharo E, Pertegal F, Pérez M, Baño l, Pérez I, Pérez E. Clorhexidina VS. Povidona Iodada como antiséptico de la piel. Universidad Miguel Hernández Facultad de Medicina. [Google Scholar][Crossref]
  8. Diomedi A, Chacón E, Delpiano L, Hervé B, Jemenao MI, Medel M, et al. Antisépticos y desinfectantes: apuntando al uso racional. Recomendaciones del Comité Consultivo de Infecciones Asociadas a la Atención de Salud, Sociedad Chilena de Infectología. Rev chil infectol. abril de. 2017; 34(2):156-74. [Google Scholar][Crossref]
  9. Isabel Gutiérrez Pérez M, Eulalia Lucio-Villegas Menéndez M, González LL, Lluch NA, Luisa Morató Agustí M, Cachafeiro SP. Uso de los antisépticos en atención primaria. Atención Primaria. mayo de. 2014; 46:10-24. [Google Scholar][Crossref]
  10. Kolasiński W. Surgical site infections - review of current knowledge, methods of prevention. Polski przeglad chirurgiczny. 2018; 91(4):41-47. https://doi.org/10.5604/01.3001.0012.7253 [Google Scholar][Crossref]
  11. Wang EW, Layon AJ. Chlorhexidine gluconates use to prevent hospital acquired infections-a useful tool, not a panacea. Ann Transl Med. enero de. 2017; 5(1):14. [Google Scholar][Crossref]
  12. Vanhoozer G, Lovern BS I, Masroor N, Abbas S, Doll M, Cooper K, et al. Chlorhexidine gluconate bathing: Patient perceptions, practices, and barriers at a tertiary care center. American Journal of Infection Control. marzo de. 2019; 47(3):349-50. [Google Scholar][Crossref]
  13. Ritter B, Herlyn PKE, Mittlmeier T, Herlyn A. Preoperative skin antisepsis using chlorhexidine may reduce surgical wound infections in lower limb trauma surgery when compared to povidone-iodine - a prospective randomized trial. American Journal of Infection Control. febrero de. 2020; 48(2):167-72. [Google Scholar][Crossref]
  14. Wagner EG, Sala JM. Uso del gluconato de clorhexidina en la curación de heridas y su potencial formación de tejido de granulación. Rev Asoc Arg Ort y Traumatol [Internet]. 30 de noviembre de 2019 [citado 12 de septiembre de 2021]; 85(2). Disponible en: http://raaot.org.ar/index.php/AAOTMAG/article/view/9 85. [Google Scholar][Crossref]

How to Cite

Cáceres, J. C. G., Pérez, A. M. G., Baez, S. J. S., Pérez, C. A. A., Galvis, M. C. C., Muñoz, M. D. M., Paez, E. R., & Emporo, A. B. (2021). Use of Chlorhexidine gluconate in wound healing and its potential formation of granulation tissue. International Journal of Medical and All Body Health Research, 2(4), 20-23.

Cáceres, Juan Camilo Gelvez, et al. "Use of Chlorhexidine gluconate in wound healing and its potential formation of granulation tissue." International Journal of Medical and All Body Health Research, vol. 2, no. 4, 2021, pp. 20-23.

Cáceres, J. C. G., Pérez, A. M. G., Baez, S. J. S., Pérez, C. A. A., Galvis, M. C. C., Muñoz, M. D. M., Paez, E. R. and Emporo, A. B. (2021) 'Use of Chlorhexidine gluconate in wound healing and its potential formation of granulation tissue', International Journal of Medical and All Body Health Research, 2(4), pp. 20-23.

Cáceres JCG, Pérez AMG, Baez SJS, Pérez CAA, Galvis MCC, Muñoz MDM, et al. Use of Chlorhexidine gluconate in wound healing and its potential formation of granulation tissue. International Journal of Medical and All Body Health Research. 2021;2(4):20-23.

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