International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

Current Issues
     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

An investigation of cancer prevention agent status in patients on haemodialysis and solid control subjects

Sabhiya Majid

Professor and Head of Department of Biochemistry, Sardar Patel Medical College, Bikaner, Rajasthan, India

Article Information

Volume / Issue2 / 3 (July-September 2021)
Pages08-10
AccessOpen Access

Publication Timeline

  • Received05 June 2021
  • Accepted30 July 2021

Full Text (PDF)

Open Access - Free to Download

Download Full Article (PDF) JATS XML

Abstract

Constant renal disappointment is a reformist loss of renal capacity over a time of months or years. Ongoing Kidney Disease (CKD) includes a range of various patho-physiological cycles related with strange Kidney capacities and a reformist decrease in glomerular filtration rate (GFR). This investigation plans to gauge the degrees of serum Malondialdehyde (MDA), Urea and Albumin in sound control subjects and in patients with constant renal infection going through haemodialysis. This was a forthcoming medical clinic based, case-control study led on 100 people matured between 25-75 years of both genders, 50 cases were taken from Nephrology Department (Dialysis Unit) as study gathering and 50 controls were sound people in PBM clinic during 2019. Blood tests of control just as study bunch were removed and broke down. The serum MDA, were assessed by UV-VIS spectrophotometer. The serum Albumin, and Serum Urea were assessed by completely autoanalyser. The aftereffects of present investigation showed that in CKD patients under-going haemodialysis serum MDA was fundamentally expanded (P-esteem <0.0001). what's more, Serum urea additionally expanded though serum egg whites level diminished in haemodialysis patients. The outcomes might be huge in understanding the conceivable commitment of previously mentioned boundaries in pathophysiological interaction of CKD, and part of cancer prevention agents in patients on haemodialysis. This investigation may help us to upgrade cell reinforcement supplementation as adjuvant treatment in treatment of renal problem patients who are onrnhaemodialysis, which will help in forestalling the approaching entanglements brought about by movement of infection and resulting Haemodialysis.

Keywords

investigation of cancer prevention

References

  1. Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A et al. GBD 2015 mortality and cause of death collaborators. Global, regional, and national life expectancy, all causes mortality and cause-specific mortality for 249 causes of deaths, 1980-2015: a systematic analysis for the global burden of disease study 2015.Lancet,2016:8:388(10053):1459-544. [Google Scholar][Crossref]
  2. Kidney disease statistic for United States. National Kidney and Urologic Diseases Information Clearinghouse 2012, 18. [Google Scholar][Crossref]
  3. Agarwal SK, Dash SC, Irshad M et al. Prevalence of chronic renal failure in adults in Delhi, India. Nephrol Dial Transplant,2005:20:1638-1642. [Google Scholar][Crossref]
  4. Kumar V, Khandelia V, Garg A. Depression and anxiety International Journal of Medical and all body Health Research http://www.allmedicaljournal.com 10 in patients with chronic kidney disease undergoing haemodialysis, Annals of Indian Psychiatry, 2018, 115-119. [Google Scholar][Crossref]
  5. Liakopoulos V, Roumeliotis S, Gorny X, Dounousi E, Mertens PR. Oxidative stress in haemodialysis patients: a review of the literature. Oxidative Med Cell Longev,2017:12:22. [Google Scholar][Crossref]
  6. Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int,2002:62:1524-38. [Google Scholar][Crossref]
  7. Houston M. The role of nutrition and nutraceutical supplements in the treatment of hypertension. World J Cardiol,2014:26:38-66. [Google Scholar][Crossref]
  8. Kim HJ, Vaziri ND. Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. Am J Physiol Renal Physiol,2009:298:F662-F671. [Google Scholar][Crossref]
  9. Vaziri ND. Roles of oxidative stress and antioxidant therapy in chronic kidney disease and hypertension. Curr Opin Nephrol Hypertens,2004:13:93-99. [Google Scholar][Crossref]
  10. Tarng DC, Wen Chen T, Huang TP, Chen CL, Liu TY, Wei YH. Increased oxidative damage to peripheral blood leukocyte DNA in chronic peritoneal dialysis patients. J Am Soc Nephrol,2002:13:132-140. [Google Scholar][Crossref]
  11. Buege JA, Aust SD. Microsomal lipid peroxidation in: Fleicher S, Packer. L, eds, method in enzymology. Academic Press, London,1978:52:302. [Google Scholar][Crossref]
  12. Roe JH, Kuether CA. Determination of ascorbic acid in whole blood and urine through the 2, 4 -Dinitrophenylhydrazine derivative of dehydroascorbic acid. J. Bio. Chem,1943:147:399. [Google Scholar][Crossref]
  13. Varley H, Gowenlock AH, Bell M. Practical clinical Biochemistry. Heinemann Medical Book,1976:2:222. [Google Scholar][Crossref]
  14. Gowenlock AH. Varley’s Practical Clinical Biochemistry. 6th edi. Butterworth- Heinemann, 1988. Chapter 19.Plasma protein; 410. [Google Scholar][Crossref]
  15. Gowenlock AH. Varley’s Practical Clinical Biochemistry. 6th edi. Butterworth- Heinemann: Chapter 17. Creatinine, Urate and Urea 1988, 350-362. [Google Scholar][Crossref]
  16. Loughrey CM, Young IS, Lightbody JH, McMaster D, McNamee PT and Trimble ER. Oxidative stress in haemodialysis, QJM: Monthly Journal of the Association of Physician,1994:87(11):679-683. [Google Scholar][Crossref]
  17. Priya R, Vasudha KC. Antioxidant vitamin in chronic renal failure. Bio Med Res,2009:20(1):1268-1272. [Google Scholar][Crossref]
  18. Guo CH, Wang CL, Chen PC, Yang TC. Linkage of some trace elements, peripheral blood lymphocytes, inflammation and oxidative stress in patients undergoing either haemodialysis or peritoneal dialysis. Biol Trace Elem Res,131(1):13-24. [Google Scholar][Crossref]
  19. Kadham A.J. Antioxidant and Lipid peroxidation in chronic renal failure patients. Al- Qadisiya Journal of Vet. Med, Sci 2008, 7(2) [Google Scholar][Crossref]

How to Cite

Majid, S. (2021). An investigation of cancer prevention agent status in patients on haemodialysis and solid control subjects. International Journal of Medical and All Body Health Research, 2(3), 08-10.

Majid, Sabhiya. "An investigation of cancer prevention agent status in patients on haemodialysis and solid control subjects." International Journal of Medical and All Body Health Research, vol. 2, no. 3, 2021, pp. 08-10.

Majid, S. (2021) 'An investigation of cancer prevention agent status in patients on haemodialysis and solid control subjects', International Journal of Medical and All Body Health Research, 2(3), pp. 08-10.

Majid S. An investigation of cancer prevention agent status in patients on haemodialysis and solid control subjects. International Journal of Medical and All Body Health Research. 2021;2(3):08-10.

Similar Articles

Share

Find this Article on

Google Scholar Semantic Scholar OpenAlex ResearchGate BASE

A newly published article may take a few days to appear on these services.