International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

Current Issues
     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Evaluation of Micronutrients and Components of Macronutrients Intake in Cardiac Patients: A Cross-sectional Study of Cardiovascular Nutritional Risk in Lahore, Pakistan

Article Information

Volume / Issue7 / 1 (January-March 2026)
Pages73-79
AccessOpen Access

Publication Timeline

  • Received01 November 2025
  • Accepted20 December 2025
  • Published

Full Text (PDF)

Open Access - Free to Download

Download Full Article (PDF) JATS XML

Abstract

Objectives: To assess micronutrients intake and evaluate macronutrients components to identify nutritional deficiencies underlying cardiovascular risks.

Methods: A simple random sampling technique was utilized. The study population consisted of cardiac patients aged 18–50 years, admitted to the inpatient department of a tertiary-care public cardiology facility. A sample size of (N=222) was calculated using OpenEpi, with a 5% margin of error and an assumed cardiovascular disease prevalence of 17.5%. A cross-sectional design was employed to obtain a snapshot of prevailing nutritional risk. Data were collected using a self-designed demographic survey and the Mini Nutritional Assessment—Short Form tool. Participants' dietary intake was analyzed using a weekly Food Frequency Questionnaire, with Cronometer software used to estimate nutrient values. Data were analyzed using IBM SPSS version 25.0, applying descriptive statistics, bivariate analysis (chi-square), and multivariate analysis of variance (MANOVA), with significance set at p < 0.05.

Results: The mean age of participants was 33.47 ± 9.44 years. The sample included 44.1% (n=98) males and 55.9% (n=124) females. Body mass index (BMI) distribution was 28.4% (n=63) underweight, 34.2% (n=76) normal weight, 28.4% (n=63) overweight, and 9.0% (n=20) obese. MANOVA indicated a statistically significant overall difference in nutrient intake profiles (Wilks’ Λ = 0.76, F(10, 428), p < 0.001). Well-nourished individuals demonstrated the highest mean intake of B vitamins, whereas malnourished individuals showed the lowest. Fat-soluble vitamin intake was also significantly higher among well-nourished individuals (Wilks’ Λ = 0.51, F(20, 418), p < 0.001). Similarly, mineral consumption differed significantly between groups, with the lowest intake observed in malnourished individuals.

Conclusion: Increased nutritional risk, associated with reduced food consumption during cardiovascular disease, was evident. Future studies are recommended to establish causal relationships between specific vitamins, minerals, and cardiovascular outcomes.

References

  1. World Health Organization. Cardiovascular diseases (CVDs) . Geneva: World Health Organization; 2025 Jul 31 . Available from: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds). [Google Scholar][Crossref]
  2. Rethemiotaki I. Global prevalence of cardiovascular diseases by gender and age during 2010-2019. Arch Med Sci Atheroscler Dis. 2023;8:e196 -205. doi:10.5114/amsad/176654. [Google Scholar][Crossref]
  3. Timmis A, Townsend N, Gale CP, Torbica A, Lettino M, Petersen SE, et al. European Society of Cardiology: cardiovascular disease statistics 2019. Eur Heart J. International Journal of Medical and All Body Health Research www.allmedicaljournal.com 2020;41(1):12-85. [Google Scholar][Crossref]
  4. Raheem A, Ahmed S, Kakar AW, Majeed H, Tareen I, Tariq K, et al. Burden of cardiovascular diseases in South Asian region from 1990 to 2019: findings from the global burden of disease study. Pak Heart J. 2022;55(1):15-21. [Google Scholar][Crossref]
  5. Samad Z, Hanif B. Cardiovascular diseases in Pakistan: imagining a postpandemic, postconflict future. Circulation. 2023;147(17):1261 -3. doi:10.1161/CIRCULATIONAHA.122.059122. [Google Scholar][Crossref]
  6. Tappia PS, Blewett H. Nutrition and cardiovascular health. Int J Mol Sci. 2020;21(7):2284. doi:10.3390/ijms21072284. [Google Scholar][Crossref]
  7. Gadgil MD, Anderson CA, Kandula NR, Kanaya AM. Dietary patterns are associated with metabolic risk factors in South Asians living in the United States. J Nutr. 2015;145(6):1211-7. doi:10.3945/jn.114.207753. [Google Scholar][Crossref]
  8. Mritunjay M, Ramavataram DVSS. Predisposing risk factors associated with acute myocardial infarction (AMI): a review. Indian J Forensic Med Toxicol. 2021;15(2):[pages not provided in query]. [Google Scholar][Crossref]
  9. Andrès E, Lorenzo-Villalba N, Terrade JE, Méndez-Bailon M. Fat-soluble vitamins A, D, E, and K: review of the literature and points of interest for the clinician. J Clin Med. 2024;13(13):3641. doi:10.3390/jcm13133641. [Google Scholar][Crossref]
  10. de la Guía-Galipienso F, Martínez-Ferran M, Vallecillo N, Lavie CJ, Sanchis-Gomar F, Pareja-Galeano H. Vitamin D and cardiovascular health. Clin Nutr. 2021;40(5):2946-57. doi:10.1016/j.clnu.2020.12.025. [Google Scholar][Crossref]
  11. US Preventive Services Task Force, Mangione CM, Barry MJ, Nicholson WK, Cabana M, Chelmow D, et al. Vitamin, mineral, and multivitamin supplementation to prevent cardiovascular disease and cancer: US Preventive Services Task Force recommendation statement. JAMA. 2022;327(23):2326 -33. doi:10.1001/jama.2022.8970. [Google Scholar][Crossref]
  12. Morelli MB, Gambardella J, Castellanos V, Trimarco V, Santulli G. Vitamin C and cardiovascular disease: an update. Antioxidants (Basel). 2020;9(12):1227. doi:10.3390/antiox9121227. [Google Scholar][Crossref]
  13. Aguilera-Méndez A, Boone-Villa D, Nieto-Aguilar R, Villafaña-Rauda S, Molina AS, Sobrevilla JV. Role of vitamins in the metabolic syndrome and cardiovascular disease. Pflugers Arch. 2022;474(1):117-40. doi:10.1007/s00424-021-02619-x. [Google Scholar][Crossref]
  14. McLean RM, Wang NX. Potassium. Adv Food Nutr Res. 2021;96:89-121. doi:10.1016/bs.afnr.2021.02.013. [Google Scholar][Crossref]
  15. Liu M, Dudley SC Jr. Magnesium, oxidative stress, inflammation, and cardiovascular disease. Antioxidants (Basel). 2020;9(10):907. doi:10.3390/antiox9100907. [Google Scholar][Crossref]
  16. Michos ED, Cainzos-Achirica M, Heravi AS, Appel LJ. Vitamin D, calcium supplements, and implications for cardiovascular health: JACC focus seminar. J Am Coll Cardiol. 2021;77(4):437 -49. doi:10.1016/j.jacc.2020.09.617. [Google Scholar][Crossref]
  17. Othon-Martínez D, Fernandez-Betances OA, Málaga-Espinoza BX, Torres-Perez ME, Cobos E, Gutierrez-Martinez C. Iron and cardiovascular health: a review. J Investig Med. 2024;72(8) :787-97. doi:10.1177/10815589241268462. [Google Scholar][Crossref]
  18. DiNicolantonio JJ, O'Keefe JH. Monounsaturated fat vs saturated fat: effects on cardio-metabolic health and obesity. Mo Med. 2022;119(1):69-73. [Google Scholar][Crossref]
  19. Evans CEL. Dietary fibre and cardiovascular health: a review of current evidence and policy. Proc Nutr Soc. 2020;79(1):61-7. doi:10.1017/S0029665119000673. [Google Scholar][Crossref]
  20. Fischer NM, Pallazola VA, Xun H, Cainzos-Achirica M, Michos ED. The evolution of the heart-healthy diet for vascular health: a walk through time. Vasc Med. 2020;25(2):184-93. doi:10.1177/1358863X19901287. [Google Scholar][Crossref]
  21. Jawad M, Maryam M, Tariq M, Khan F. Screening, assessment and evaluation of macronutrients & their components intake among cardiac patients at tertiary care hospital of Lahore. Int J Pharm Integr Health Sci. 2024;5(2). doi:10.56536/ijpihs.v5i2.136. [Google Scholar][Crossref]
  22. Jarosz I, Gorecki K, Kalisz G, Popiolek-Kalisz J. Nutritional status assessment tools in cardiovascular patients. Nutrients. 2025;17(16):2703. doi:10.3390/nu17162703. [Google Scholar][Crossref]
  23. Zhou YQ, He WM, Jing S, Xie YQ, Chen S, Li JN. Comparing GLIM and SGA nutritional criteria for malnutrition assessment and prognosis in chronic heart failure patients. Int J Gen Med. 2025;18:1669-79. doi:10.2147/IJGM.S514143. [Google Scholar][Crossref]
  24. Steinberg JR, Turner BE, Weeks BT, Magnani CJ, Wong BO, Rodriguez F, et al. Analysis of female enrollment and participant sex by burden of disease in US clinical trials between 2000 and 2020. JAMA Netw Open. 2021;4(6):e2113749. doi:10.1001/jamanetworkopen.2021.13749. [Google Scholar][Crossref]
  25. Held C, Hadziosmanovic N, Aylward PE, Hagström E, Hochman JS, Stewart RA, et al. Body mass index and association with cardiovascular outcomes in patients with stable coronary heart disease: a STABILITY substudy. J Am Heart Assoc. 2022;11(3):e023667. doi:10.1161/JAHA.121.023667. [Google Scholar][Crossref]
  26. Wang ZJ, Zhou YJ, Galper BZ, Gao F, Yeh RW, Mauri L. Association of body mass index with mortality and cardiovascular events for patients with coronary artery disease: a systematic review and meta-analysis. Heart. 2015;101(20):1631-8. [Google Scholar][Crossref]
  27. Wei S, Nguyen TT, Zhang Y, Ryu D, Gariani K. Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management. Front Endocrinol (Lausanne). 2023;14:1185221. doi:10.3389/fendo.2023.1185221. [Google Scholar][Crossref]
  28. Ma C, Ho SK, Singh S, Choi MY. Gender disparities in food security, dietary intake, and nutritional health in the United States. Am J Gastroenterol. 2021;116(3):584-92. [Google Scholar][Crossref]
  29. Kwaśny A, Uchmanowicz I, Juárez-Vela R, Młynarska A, Łokieć K, Czapla M. Sex-related differences in the impact of nutritional status on in-hospital mortality in heart failure: a retrospective cohort study. Eur J Cardiovasc Nurs. 2024;23(2):176-87. [Google Scholar][Crossref]
  30. Brandt EJ, Leung CW, Chang T, Ayanian JZ, Banerjee M, Kirch M, et al. Differences in US adult dietary patterns by cardiometabolic health and socioeconomic vulnerability. J Nutr. 2025 Jun 9. doi:10.1016/j.tjnut.2025.05.012. [Note: Exact DOI may vary; based on query details.] [Google Scholar][Crossref]
  31. Koemel NA, Senior AM, Laouali N, Celermajer DS, Grech A, Parker HM, et al. Associations between dietary macronutrient composition and cardiometabolic health: data from NHANES 1999 –2014. Eur J Nutr. 2025;64(1):41. [Note: Volume/issue adjusted per standard.] [Google Scholar][Crossref]
  32. Miao Y, Guo Y, Chen Y, Lin Y, Lu Y, Guo Q. The effect International Journal of Medical and All Body Health Research www.allmedicaljournal.com of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis. Nutr Rev. 2024;82(10):1386-401. [Google Scholar][Crossref]
  33. Wu Y, Li S, Wang W, Zhang D. Associations of dietary vitamin B1, vitamin B2, niacin, vitamin B6, vitamin B12 and folate equivalent intakes with metabolic syndrome. Int J Food Sci Nutr. 2020;71(6):738-49. [Google Scholar][Crossref]
  34. Godinez Flores T, Barron C, Payró G, Castillo Martinez LI. Inadequate calorie and macronutrient intake in a population with congestive heart failure in a non-cardiovascular tertiary hospital. Circulation. 2024;150(Suppl_1):A4119926. [Google Scholar][Crossref]
  35. Aliasgharpour M. Fat soluble vitamins role in health promotion. J Emerg Health Care. 2022;11(4):49-68. [Google Scholar][Crossref]
  36. Haugsgjerd TR, Egeland GM, Nygård OK, Vinknes KJ, Sulo G, Lysne V, et al. Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort. BMJ Open. 2020;10(5):e035953. doi:10.1136/bmjopen-2019-035953. [Google Scholar][Crossref]
  37. Moser MA, Chun OK. Vitamin C and heart health: a review based on findings from epidemiologic studies. Int J Mol Sci. 2016;17(8):1328. doi:10.3390/ijms17081328. [Google Scholar][Crossref]
  38. Bansal N, Alharbi A, Shah M, Altorok I, Assaly R, Altorok N. Impact of malnutrition on the outcomes in patients admitted with heart failure. J Clin Med. 2024;13(14):4215. [Google Scholar][Crossref]
  39. Duan C, Lv M, Shou X, Chen Z, Luan Y, Hu Y. Associations between nine dietary minerals intake and all-cause mortality in individuals with atherosclerotic cardiovascular disease. Front Nutr. 2024;11:1447167. doi:10.3389/fnut.2024.1447167. [Google Scholar][Crossref]

How to Cite

Komal, M., Jawad, M., Malik, Z., Ahmed, S., Shafique, M., Afzal, M., Khan, F., Shahzad, I., & Saad, M. (2026). Evaluation of Micronutrients and Components of Macronutrients Intake in Cardiac Patients: A Cross-sectional Study of Cardiovascular Nutritional Risk in Lahore, Pakistan. International Journal of Medical and All Body Health Research, 7(1), 73-79. https://doi.org/10.54660/IJMBHR.2026.7.1.73-79

Komal, Muteeba, et al. "Evaluation of Micronutrients and Components of Macronutrients Intake in Cardiac Patients: A Cross-sectional Study of Cardiovascular Nutritional Risk in Lahore, Pakistan." International Journal of Medical and All Body Health Research, vol. 7, no. 1, 2026, pp. 73-79. https://doi.org/10.54660/IJMBHR.2026.7.1.73-79.

Komal, M., Jawad, M., Malik, Z., Ahmed, S., Shafique, M., Afzal, M., Khan, F., Shahzad, I. and Saad, M. (2026) 'Evaluation of Micronutrients and Components of Macronutrients Intake in Cardiac Patients: A Cross-sectional Study of Cardiovascular Nutritional Risk in Lahore, Pakistan', International Journal of Medical and All Body Health Research, 7(1), pp. 73-79. doi: 10.54660/IJMBHR.2026.7.1.73-79.

Komal M, Jawad M, Malik Z, Ahmed S, Shafique M, Afzal M, et al. Evaluation of Micronutrients and Components of Macronutrients Intake in Cardiac Patients: A Cross-sectional Study of Cardiovascular Nutritional Risk in Lahore, Pakistan. International Journal of Medical and All Body Health Research. 2026;7(1):73-79. doi:10.54660/IJMBHR.2026.7.1.73-79

Share

Find this Article on

Google Scholar Semantic Scholar OpenAlex Scilit Crossref ResearchGate BASE

A newly published article may take a few days to appear on these services.