International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

Current Issues
     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

An Unusual Case of Optic Atrophy in a Child due to Intracranial Space Occupying Lesion

Dr. Mohit Srivastava, Dr. Anshu Sharma, Dr. Shikha Pawaiya, Dr. Gargi Bhalla

PG Resident, Department of Ophthalmology, Rama Medical College and Hospital, Hapur, Uttar Pradesh- 245304, India; Principal, Rama Medical College and Hospital, Hapur, Uttar Pradesh- 245304, India; Head of Department, Department of Ophthalmology, Rama Medical College and Hospital, Hapur, Uttar Pradesh- 245304, India; Consultant, Sant Trivenigiri Puranjyoti Eye Hospital, Bhatinda, Punjab, India

Article Information

Volume / Issue6 / 4 (October-December 2025)
Pages129-132
AccessOpen Access

Publication Timeline

  • Received03 October 2025
  • Accepted05 November 2025
  • Published

Full Text (PDF)

Open Access - Free to Download

Download Full Article (PDF) JATS XML

Abstract

Optic atrophy is an irreversible end stage of optic nerve damage and is frequently associated with serious intracranial pathology. Ocular manifestations often serve as early indicators of intracranial space occupying lesions (ICSOL), aiding in lesion localization and timely intervention. This case report describes a 9-year-old female who presented with gradually progressive, painless visual loss in the left eye accompanied by headache and systemic symptoms such as fever, weight loss, and seizures. Ophthalmic evaluation revealed relative afferent pupillary defect and optic atrophy in the affected eye, with disc pallor in the fellow eye. Neuroimaging demonstrated an ill-defined conglomerated lesion in the left parieto-occipital region with midline shift and leptomeningeal enhancement, suggestive of tuberculoma. Further investigations, including positive Mantoux test, cerebrospinal fluid analysis, and biopsy findings of necrotic brain parenchyma with giant cell granulomas, confirmed the diagnosis. The patient underwent decompressive craniotomy followed by anti-tubercular therapy and steroids. This report highlights tuberculoma as an uncommon but important cause of compressive optic neuropathy in children. Early recognition of ocular signs and prompt multidisciplinary management are crucial, as visual recovery is possible before the development of optic atrophy. Once optic atrophy is established, visual loss remains permanent.

Keywords

Optic AtrophyIntracranial Space Occupying LesionTuberculomaCompressive Optic Neuropathy

References

  1. Chinta S, Wallang BS, Sachdeva V, Gupta A, Patil-Chhablani P, Kekunnaya R. Etiology and clinical profile of childhood optic nerve atrophy at a tertiary eye care center in South India. Indian J Ophthalmol. 2014 Oct;62(10):1003-7. [Google Scholar][Crossref]
  2. Bajracharya K, Gautam P, Yadav SK, Shrestha N. Epidemiology and causes of optic atrophy in general outpatient department of Lumbini Eye Institute. Journal of Universal College of Medical Sciences. 2015;3(2):26-9. [Google Scholar][Crossref]
  3. Repka MX, Miller NR. Optic atrophy in children. Am J Ophthalmol. 1988 Aug 1;106(2):191-3. [Google Scholar][Crossref]
  4. Nalawade KV, Javadekar SD. Clinical study of ocular manifestations of intracranial space occupying lesions. J Evol Med Dent Sci. 2017;6(29):2251-7. [Google Scholar][Crossref]
  5. Krishna Naidu. Aetio pathogenesis of optic atrophy: case study. International Journal of Scientific Research and Management. 2015;3(3):2369-77. [Google Scholar][Crossref]

How to Cite

Srivastava, M., Sharma, A., Pawaiya, S., & Bhalla, G. (2025). An Unusual Case of Optic Atrophy in a Child due to Intracranial Space Occupying Lesion. International Journal of Medical and All Body Health Research, 6(4), 129-132. https://doi.org/10.54660/IJMBHR.2025.6.4.129-132

Srivastava, Mohit, et al. "An Unusual Case of Optic Atrophy in a Child due to Intracranial Space Occupying Lesion." International Journal of Medical and All Body Health Research, vol. 6, no. 4, 2025, pp. 129-132. https://doi.org/10.54660/IJMBHR.2025.6.4.129-132.

Srivastava, M., Sharma, A., Pawaiya, S. and Bhalla, G. (2025) 'An Unusual Case of Optic Atrophy in a Child due to Intracranial Space Occupying Lesion', International Journal of Medical and All Body Health Research, 6(4), pp. 129-132. doi: 10.54660/IJMBHR.2025.6.4.129-132.

Srivastava M, Sharma A, Pawaiya S, Bhalla G. An Unusual Case of Optic Atrophy in a Child due to Intracranial Space Occupying Lesion. International Journal of Medical and All Body Health Research. 2025;6(4):129-132. doi:10.54660/IJMBHR.2025.6.4.129-132

Similar Articles

Share

Find this Article on

Google Scholar Semantic Scholar OpenAlex Scilit Crossref ResearchGate BASE

A newly published article may take a few days to appear on these services.