International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

Current Issues
     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Leveraging Algorithmic and Machine Learning Technologies for Breast Cancer Management in Sub-Saharan Africa

Article Information

Volume / Issue3 / 4 (October-December 2022)
Pages107-121
AccessOpen Access

Publication Timeline

  • Received10 November 2022
  • Accepted12 December 2022

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Abstract

Due to delayed diagnosis, few treatment choices, and inadequate healthcare infrastructure, breast cancer continues to be a major worldwide health concern, with some of the greatest fatality rates occurring in Sub-Saharan Africa. By improving the treatment of breast cancer, machine learning (ML) and algorithmic technologies provide a game-changing chance to solve these issues. This study examines the current state of breast cancer in Sub-Saharan Africa, emphasizing the disease's startling prevalence and death rates as well as the structural and systemic obstacles to quality care, such as a lack of diagnostic resources, restricted access to treatment, and socioeconomic considerations. ML has a lot of potential in the medical field, especially in the areas of breast cancer early detection, diagnosis, and therapy planning. Medical image analysis and patient prediction have shown the effectiveness of machine learning models, including supervised, unsupervised, and reinforcement learning methods. However, implementing these technologies in Sub-Saharan Africa requires overcoming several barriers, including poor data availability, limited infrastructure, and a shortage of trained professionals. This paper highlights the importance of partnerships between governments, international organizations, and the tech industry in bridging these gaps. Recommendations include improving healthcare infrastructure, training healthcare workers, and developing region-specific ML models using local datasets to ensure cultural and contextual relevance. Addressing ethical concerns, such as data privacy and equitable access, is also emphasized to ensure the sustainable and inclusive adoption of these technologies. By leveraging ML and algorithmic technologies, Sub-Saharan Africa has the potential to significantly improve breast cancer outcomes, reduce mortality rates, and build a more robust and equitable healthcare system. Continued research, investment, and collaboration will be pivotal in achieving this vision.

References

  1. Achilonu OJ, Singh E, Nimako G, Eijkemans RM, Musenge E. Rule‐based information extraction from free‐text pathology reports reveals trends in South African female breast cancer molecular subtypes and Ki67 expression. BioMed Res Int. 2022;2022(1):6157861. [Google Scholar][Crossref]
  2. Adeoye J, Akinshipo A, Koohi-Moghadam M, Thomson P, Su YX. Construction of machine learning-based models for cancer outcomes in low and lower-middle income countries: A scoping review. Front Oncol. 2022;12:976168. [Google Scholar][Crossref]
  3. Ahmad MAB. Mining health data for breast cancer diagnosis using machine learning [dissertation]. Canberra (AU): University of Canberra; 2013. [Google Scholar][Crossref]
  4. Akuoko DE. Big data for better breast cancer treatment [master’s thesis]. Manchester (UK): The University of Manchester; 2020. [Google Scholar][Crossref]
  5. Alli OI, Dada SA. Pharmacist-led smoking cessation programs: A comprehensive review of effectiveness, implementation models, and future directions. Int J Sci Technol Res Arch. 2022;3(2):297–304. Available from: https://doi.org/10.53771/ijstra.2022.3.2.0129 [Google Scholar][Crossref]
  6. Alli OI, Dada SA. Innovative models for tobacco dependency treatment: A review of advances in integrated care approaches in high-income healthcare systems. IRE J. 2021;5(6):273–282. ISSN: 2456-8880. [Google Scholar][Crossref]
  7. Ampatzis C, Zervoudis S, Iatrakis G, Mastorakos G. Effect of oral contraceptives on bone mineral density. Acta Endocrinol (Buchar). 2022;18(3):355. [Google Scholar][Crossref]
  8. Beaber EF, Buist DS, Barlow WE, Malone KE, Reed SD, Li CI. Recent oral contraceptive use by formulation and breast cancer risk among women 20 to 49 years of age. Cancer Res. 2014;74(15):4078–89. [Google Scholar][Crossref]
  9. Benagiano G, Bastianelli C, Farris M. Contraception today. Ann N Y Acad Sci. 2006;1092(1):1–32. [Google Scholar][Crossref]
  10. Boppart SA, Richards-Kortum R. Point-of-care and point-of-procedure optical imaging technologies for primary care and global health. Sci Transl Med. 2014;6(253):253rv2. [Google Scholar][Crossref]
  11. Boyd NF, Melnichouk O, Martin LJ, Hislop G, Chiarelli AM, Yaffe MJ, Minkin S. Mammographic density, response to hormones, and breast cancer risk. J Clin International Journal of Medical and All Body Health Research www.allmedicaljournal.com Oncol. 2011;29(22):2985–92. [Google Scholar][Crossref]
  12. Brooks JD, Nabi H, Andrulis IL, Antoniou AC, Chiquette J, Després P, Simard J. Personalized risk assessment for prevention and early detection of breast cancer: Integration and implementation (PERSPECTIVE I&I). J Pers Med. 2021;11(6):511. [Google Scholar][Crossref]
  13. Burke MM. Functional polymorphisms in the epidermal growth factor family genes and their relationship to the risk and severity of breast cancer [doctoral dissertation]. Manchester (UK): The University of Manchester; 2010. [Google Scholar][Crossref]
  14. Burkman R, Bell C, Serfaty D. The evolution of combined oral contraception: Improving the risk-to-benefit ratio. Contraception. 2011;84(1):19–34. [Google Scholar][Crossref]
  15. Cancino RS, Su Z, Mesa R, Tomlinson GE, Wang J. The impact of COVID-19 on cancer screening: Challenges and opportunities. JMIR Cancer. 2020;6(2):e21697. [Google Scholar][Crossref]
  16. Chalfant JS, Hoyt AC. Breast density: Current knowledge, assessment methods, and clinical implications. J Breast Imaging. 2022;4(4):357–70. [Google Scholar][Crossref]
  17. Christin-Maitre S. History of oral contraceptive drugs and their use worldwide. Best Pract Res Clin Endocrinol Metab. 2013;27(1):3–12. [Google Scholar][Crossref]
  18. Chui M, Harryson M, Valley S, Manyika J, Roberts R. Notes from the AI frontier: Applying AI for social good [Internet]. 2018 [cited 2024 Feb 10]. Available from: https://www.mckinsey.com [Google Scholar][Crossref]
  19. Cipriani S, Todisco T, Scavello I, Di Stasi V, Maseroli E, Vignozzi L. Obesity and hormonal contraception: An overview and a clinician’s practical guide. Eat Weight Disord Stud Anorexia Bulimia Obes. 2020;25:1129–40. [Google Scholar][Crossref]
  20. Crouch BT, Gallagher J, Wang R, Duer J, Hall A, Soo MS, Ramanujam N. Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer. Sci Rep. 2019;9(1):3461. [Google Scholar][Crossref]
  21. Dalene Skarping I. Mammographic density: A marker of treatment outcome in breast cancer? [doctoral dissertation]. Lund (SE): Lund University; 2020. [Google Scholar][Crossref]
  22. Dannhauser A, Van den Berg VL. Prevalence of the known risk factors in women diagnosed with breast cancer at Queen II Hospital, Maseru [doctoral dissertation]. Bloemfontein (ZA): University of the Free State; 2011. [Google Scholar][Crossref]
  23. De Hert M, Peuskens J, Sabbe T, Mitchell AJ, Stubbs B, Neven P, Detraux J. Relationship between prolactin, breast cancer risk, and antipsychotics in patients with schizophrenia: A critical review. Acta Psychiatr Scand. 2016;133(1):5–22. [Google Scholar][Crossref]
  24. De Leo V, Musacchio MC, Cappelli V, Piomboni P, Morgante G. Hormonal contraceptives: Pharmacology tailored to women's health. Hum Reprod Update. 2016;22(5):634–46. [Google Scholar][Crossref]
  25. Del Pup L, Codacci-Pisanelli G, Peccatori F. Breast cancer risk of hormonal contraception: Counselling considering new evidence. Crit Rev Oncol Hematol. 2019;137:123–30. [Google Scholar][Crossref]
  26. Dias JA, Fredrikson GN, Ericson U, Gullberg B, Hedblad B, Engström G, Wirfält E. Low-grade inflammation, oxidative stress and risk of invasive post-menopausal breast cancer: A nested case-control study within the Malmö diet and cancer study. Breast Cancer Res Treat. 2016;155(1):63–70. [Google Scholar][Crossref]
  27. Dias JA, Fredrikson GN, Ericson U, Gullberg B, Hedblad B, Engström G, et al. Low-grade inflammation, oxidative stress and risk of invasive post-menopausal breast cancer—a nested case-control study from the Malmö Diet and Cancer Cohort. PLOS ONE. 2016;11(7):e0158959. [Google Scholar][Crossref]
  28. Dragoman MV. The combined oral contraceptive pill— recent developments, risks and benefits. Best Practice & Research Clinical Obstetrics & Gynaecology. 2014;28(6):825-34. [Google Scholar][Crossref]
  29. Elebro K. Androgen and Estrogen Receptors in Breast Cancer: Impact on Risk, Prognosis and Treatment Prediction [dissertation]. 2017. [Google Scholar][Crossref]
  30. Elkefi S, Layeb SB. Artificial intelligence and operations research in a middle ground to support decision-making in healthcare systems in Africa. Africa Case Studies in Operations Research: A Closer Look into Applications and Algorithms. 2022;51-69. [Google Scholar][Crossref]
  31. Feng MX, Hong JX, Wang Q, Fan YY, Yuan CT, Lei XH, et al. Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast cancer cells and osteoclasts. Scientific Reports. 2016;6(1):19074. [Google Scholar][Crossref]
  32. Fischer A. Life Events, Perceived Stress and Breast Cancer Risk in the Hereditary Breast and Ovarian Cancer Study of Orange County, CA [dissertation]. UC Irvine; 2016. [Google Scholar][Crossref]
  33. García Damián A. Disease Biomarkers in Metabolomics. 2020. [Google Scholar][Crossref]
  34. Grindlay K, Burns B, Grossman D. Prescription requirements and over-the-counter access to oral contraceptives: a global review. Contraception. 2013;88(1):91-6. [Google Scholar][Crossref]
  35. Gupta A, Anand A, Hasija Y. Recall-based machine learning approach for early detection of cervical cancer. In: 2021 6th International Conference for Convergence in Technology (I2CT). IEEE; 2021. p. 1-5. [Google Scholar][Crossref]
  36. Hager E, Chen J, Zhao L. Minireview: parabens exposure and breast cancer. International Journal of Environmental Research and Public Health. 2022;19(3):1873. [Google Scholar][Crossref]
  37. Hampson E. A brief guide to the menstrual cycle and oral contraceptive use for researchers in behavioral endocrinology. Hormones and Behavior. 2020;119:104655. [Google Scholar][Crossref]
  38. Haney K, Tandon P, Divi R, Ossandon MR, Baker H, Pearlman PC. The role of affordable, point-of-care technologies for cancer care in low-and middle-income countries: a review and commentary. IEEE Journal of Translational Engineering in Health and Medicine. 2017;5:1-14. [Google Scholar][Crossref]
  39. Harvey JA, Bovbjerg VE. Quantitative assessment of mammographic breast density: relationship with breast cancer risk. Radiology. 2004;230(1):29-41. [Google Scholar][Crossref]
  40. Harz M. Complexity Reduction in Image-Based Breast Cancer Care [dissertation]. Staats -und Universitätsbibliothek Bremen; 2014. [Google Scholar][Crossref]
  41. Hasyim NA. MAGEB2 Antibody as Potential Diagnostic and Predictive Tool in the Progression of Oral Cancer [master’s thesis]. University of Malaya (Malaysia); 2020. [Google Scholar][Crossref]
  42. Helland T. Tamoxifen in the Treatment of Luminal Breast Cancer: Implications of Active Metabolites on Gene Expression, Side Effects and Clinical Outcome. 2019. [Google Scholar][Crossref]
  43. Ikerionwu C, Ugwuishiwu C, Okpala I, James I, Okoronkwo M, Nnadi C, et al. Application of machine and deep learning algorithms in optical microscopic International Journal of Medical and All Body Health Research www.allmedicaljournal.com detection of Plasmodium: A malaria diagnostic tool for the future. Photodiagnosis and Photodynamic Therapy. 2022;40:103198. [Google Scholar][Crossref]
  44. Kanadys W, Barańska A, Malm M, Błaszczuk A, Polz-Dacewicz M, Janiszewska M, et al. Use of oral contraceptives as a potential risk factor for breast cancer: a systematic review and meta-analysis of case-control studies up to 2010. International Journal of Environmental Research and Public Health. 2021;18(9):4638. [Google Scholar][Crossref]
  45. Kennedy CE, Yeh PT, Gonsalves L, Jafri H, Gaffield ME, Kiarie J, et al. Should oral contraceptive pills be available without a prescription? A systematic review of over-the-counter and pharmacy access availability. BMJ Global Health. 2019;4(3):e001402. [Google Scholar][Crossref]
  46. Kimera R, Kaggwa F, Mwavu R, Mugonza R, Tumuhimbise W, Munguci G, et al. Mbarara University of Science and Technology (MUST). Leveraging Data Science for Global Health. 2020;329. [Google Scholar][Crossref]
  47. Kimera R, Kaggwa F, Mwavu R, Mugonza R, Tumuhimbise W, Munguci G, et al. An overview of data science innovations, challenges and limitations towards real-world implementations in global health. 2020. [Google Scholar][Crossref]
  48. Kiyasseh D, Zhu T, Clifton D. The promise of clinical decision support systems targeting low-resource settings. IEEE Reviews in Biomedical Engineering. 2020;15:354-71. [Google Scholar][Crossref]
  49. Kumar N. Application of Machine Learning for Breast Cancer Diagnosis [dissertation]. MNIT Jaipur; 2019. [Google Scholar][Crossref]
  50. Kurta ML. Ovarian Cancer Epidemiology: Risk, Diagnosis, and Prognosis [dissertation]. University of Pittsburgh; 2013. [Google Scholar][Crossref]
  51. Li MX, Sun XM, Cheng WG, Ruan HJ, Liu K, Chen P, et al. Using a machine learning approach to identify key prognostic molecules for esophageal squamous cell carcinoma. BMC Cancer. 2021;21:1-11. [Google Scholar][Crossref]
  52. Liu ZYC, Chamberlin AJ, Tallam K, Jones IJ, Lamore LL, Bauer J, et al. Deep learning segmentation of satellite imagery identifies aquatic vegetation associated with snail intermediate hosts of schistosomiasis in Senegal, Africa. Remote Sensing. 2022;14(6):1345. [Google Scholar][Crossref]
  53. Mahboobnia K, Pirro M, Marini E, Grignani F, Bezsonov EE, Jamialahmadi T, et al. PCSK9 and cancer: Rethinking the link. Biomedicine & Pharmacotherapy. 2021;140:111758. [Google Scholar][Crossref]
  54. Marchbanks PA, Curtis KM, Mandel MG, Wilson HG, Jeng G, Folger SG, et al. Oral contraceptive formulation and risk of breast cancer. Contraception. 2012;85(4):342-50. [Google Scholar][Crossref]
  55. Masarwah A. Mammographic breast density, tumour characteristics and the expression of hyaluronan as prognostic surrogate markers for breast cancer [dissertation]. Itä-Suomen yliopisto; 2016. [Google Scholar][Crossref]
  56. Mathew A, Doorenbos AZ, Li H, Jang MK, Park CG, Bronas UG. Allostatic load in cancer: a systematic review and mini meta-analysis. Biol Res Nurs. 2021;23(3):341-61. [Google Scholar][Crossref]
  57. Monteiro AC, Leal AC, Gonçalves-Silva T, Mercadante ACT, Kestelman F, Chaves SB, et al. T cells induce pre-metastatic osteolytic disease and help bone metastases establishment in a mouse model of metastatic breast cancer. PLoS One. 2013;8(7):e68171. [Google Scholar][Crossref]
  58. Moore JX, Han Y, Appleton C, Colditz G, Toriola AT. Determinants of mammographic breast density by race among a large screening population. JNCI Cancer Spectr. 2020;4(2):pkaa010. [Google Scholar][Crossref]
  59. Mørch LS, Skovlund CW, Hannaford PC, Iversen L, Fielding S, Lidegaard Ø. Contemporary hormonal contraception and the risk of breast cancer. N Engl J Med. 2017;377(23):2228-39. [Google Scholar][Crossref]
  60. Moyo D. Breast and cervical cancer prediction using supervised machine learning algorithms. 2022. [Google Scholar][Crossref]
  61. Mu T. Design of machine learning algorithms with applications to breast cancer detection [dissertation]. University of Liverpool; 2008. [Google Scholar][Crossref]
  62. Mulukuntla S, Gaddam M. Overcoming barriers to equity in healthcare access: innovative solutions through technology. EPH-Int J Med Health Sci. 2017;3(1):51-60. [Google Scholar][Crossref]
  63. National Academies of Sciences, Engineering, and Medicine. Optimizing the patient journey by leveraging advances in health care. In: Crossing the Global Quality Chasm: Improving Health Care Worldwide. National Academies Press (US); 2018. [Google Scholar][Crossref]
  64. Neeman E, Lyon L, Sun H, Conell C, Reed M, Kumar D, et al. Future of teleoncology: trends and disparities in telehealth and secure message utilization in the COVID-19 era. JCO Clin Cancer Inform. 2022;6:e2100160. [Google Scholar][Crossref]
  65. Ngwa W, Olver I, Schmeler KM. The use of health-related technology to reduce the gap between developed and undeveloped regions around the globe. Am Soc Clin Oncol Educ Book. 2020;40:227-36. [Google Scholar][Crossref]
  66. Oliveira B, Jones E, Glavin M, O’Halloran M. Towards improved breast cancer diagnosis using microwave technology and machine learning [dissertation]. Ph.D. thesis, NUI Galway; 2018. [Google Scholar][Crossref]
  67. Oskar S. Exposure to phthalates during critical windows of susceptibility and breast tissue composition: implications for breast cancer risk. Columbia University; 2021. [Google Scholar][Crossref]
  68. Pai V, Baker H, Lash TB. The National Institutes of Health Affordable Cancer Technologies Program: improving access to resource-appropriate technologies for cancer detection, diagnosis, monitoring, and treatment in low- and middle-income countries. 2016. [Google Scholar][Crossref]
  69. Pan L, Feng Z, Peng S. A review of machine learning approaches, challenges and prospects for computational tumor pathology. arXiv preprint arXiv:2206.01728. 2022. [Google Scholar][Crossref]
  70. Pareek PK, Surendhar SP, Prasad R, Ramkumar G, Dixit E, Subbiah R, et al. [Retracted] Predicting the spread of vessels in initial-stage cervical cancer through radiomics strategy based on deep learning approach. Adv Mater Sci Eng. 2022;2022(1):1008652. [Google Scholar][Crossref]
  71. Passey A. Epigenetic biomarkers for clinical outcomes and mechanisms driving emergence of drug resistance in ovarian cancer [dissertation]. Imperial College London; 2017. [Google Scholar][Crossref]
  72. Patel MI, Ferguson JM, Castro E, Pereira-Estremera CD, Armaiz-Peña GN, Duron Y, et al. Racial and ethnic disparities in cancer care during the COVID-19 pandemic. JAMA Netw Open. 2022;5(7):e2222009. [Google Scholar][Crossref]
  73. Quinn J. Evaluation of the role of autophagy in ovarian cancer chemoresistance. 2020. [Google Scholar][Crossref]
  74. Rajaneesh N. Risk factors in breast cancer: work on preventing recurrence. Notion Press; 2021. [Google Scholar][Crossref]
  75. Ramanujam N, Crouch B. Democratizing cancer diagnostics and therapeutics through precision medicine. Technol Innov. 2019;20(4):399-413. International Journal of Medical and All Body Health Research www.allmedicaljournal.com [Google Scholar][Crossref]
  76. Ramón y Cajal T, Chirivella I, Miranda J, Teule A, Izquierdo Á, Balmaña J, et al. Mammographic density and breast cancer in women from high-risk families. Breast Cancer Res. 2015;17:1-11. [Google Scholar][Crossref]
  77. Renner RM, Jensen JT. Progestin‐only oral contraceptive pills. Contraception. 2011;40-56. [Google Scholar][Crossref]
  78. Riondino S, Ferroni P, Zanzotto FM, Roselli M, Guadagni F. Predicting VTE in cancer patients: candidate biomarkers and risk assessment models. Cancers. 2019;11(1):95. [Google Scholar][Crossref]
  79. Saleh M, Naik G, Mwirigi A, Shaikh AJ, Sayani S, Ghesani M, et al. Bridging the gap in training and clinical practice in Sub-Saharan Africa. Curr Breast Cancer Rep. 2019;11:158-69. [Google Scholar][Crossref]
  80. Samson ME. Progesterone-only oral contraceptive pill, breast cancer, heart disease, and stroke. 2016. [Google Scholar][Crossref]
  81. Santen RJ, Allred DC, Ardoin SP, Archer DF, Boyd N, Braunstein GD, et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab. 2010;95(7_supplement_1):s1-66. [Google Scholar][Crossref]
  82. Santosh KC, Gaur L. Artificial intelligence and machine learning in public healthcare: opportunities and societal impact. Springer Nature; 2022. [Google Scholar][Crossref]
  83. Seo BR, Bhardwaj P, Choi S, Gonzalez J, Andresen Eguiluz RC, Wang K, et al. Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis. Sci Transl Med. 2015;7(301):301ra130. [Google Scholar][Crossref]
  84. Shah D, Patil M, National PCOS Working Group. Consensus statement on the use of oral contraceptive pills in polycystic ovarian syndrome women in India. J Hum Reprod Sci 2018;11(2):96-118. [Google Scholar][Crossref]
  85. Shaikh K, Krishnan S, Thanki RM. Artificial intelligence in breast cancer early detection and diagnosis. Cham: Springer; 2021. p. 209-49. [Google Scholar][Crossref]
  86. Shubbar S. Ultrasound medical imaging systems using telemedicine and blockchain for remote monitoring of responses to neoadjuvant chemotherapy in women’s breast cancer: concept and implementation [Master's thesis]. Kent State Univ; 2017. [Google Scholar][Crossref]
  87. Shukla AK, Jamwal R, Bala K. Adverse effect of combined oral contraceptive pills. Asian J Pharm Clin Res 2017;10:17-21. [Google Scholar][Crossref]
  88. Shukla AK, Jamwal R, Bala K. Adverse effect of combined oral contraceptive pills. Asian J Pharm Clin Res 2017;10:17-21. [Google Scholar][Crossref]
  89. Sitruk-Ware R, Nath A, Mishell DR Jr. Contraception technology: past, present and future. Contraception 2013;87(3):319-30. [Google Scholar][Crossref]
  90. Stanczyk FZ, Archer DF, Bhavnani BR. Ethinyl estradiol and 17β-estradiol in combined oral contraceptives: pharmacokinetics, pharmacodynamics, and risk assessment. Contraception 2013;87(6):706-27. [Google Scholar][Crossref]
  91. Tenti S, Correale P, Cheleschi S, Fioravanti A, Pirtoli L. Aromatase inhibitors—induced musculoskeletal disorders: current knowledge on clinical and molecular aspects. Int J Mol Sci 2020;21(16):5625. [Google Scholar][Crossref]
  92. Tesic V, Kolaric B, Znaor A, Kuna SK, Brkljacic B. Mammographic density and estimation of breast cancer risk in intermediate risk population. Breast J 2013;19(1):71-8. [Google Scholar][Crossref]
  93. Thomford NE, Bope CD, Agamah FE, Dzobo K, Owusu Ateko R, Chimusa E, et al. Implementing artificial intelligence and digital health in resource-limited settings? Top 10 lessons we learned in congenital heart defects and cardiology. Omics 2020;24(5):264-77. [Google Scholar][Crossref]
  94. Thompson PA, Preece C, Stopeck AT. Breast cancer prevention. In: Fundamentals of cancer prevention. Springer; 2019. p. 543-606. [Google Scholar][Crossref]
  95. Upadhya KK, Santelli JS, Raine-Bennett TR, Kottke MJ, Grossman D. Over-the-counter access to oral contraceptives for adolescents. J Adolesc Health 2017;60(6):634-40. [Google Scholar][Crossref]
  96. Van der Westhuizen E, Van der Merwe E. The safety and efficacy of low-dose oral contraceptives: CPD article. S Afr Fam Pract 2011;53(5):403-11. [Google Scholar][Crossref]
  97. Verma N, Cwiak C, Kaunitz AM. Hormonal contraception: systemic estrogen and progestin preparations. Clin Obstet Gynecol 2021;64(4):721-38. [Google Scholar][Crossref]
  98. Waljee AK, Weinheimer-Haus EM, Abubakar A, Ngugi AK, Siwo GH, Kwakye G, et al. Artificial intelligence and machine learning for early detection and diagnosis of colorectal cancer in sub-Saharan Africa. Gut 2022;71(7):1259-65. [Google Scholar][Crossref]
  99. Westbrook K, Stearns V. Pharmacogenomics of breast cancer therapy: an update. Pharmacol Ther 2013;139(1):1-11. [Google Scholar][Crossref]
  100. White A. Multiple sources of PAH exposure, DNA methylation and breast cancer. [Unpublished thesis]. 2015. [Google Scholar][Crossref]
  101. White ND. Hormonal contraception and breast cancer risk. Am J Lifestyle Med 2018;12(3):224-6. [Google Scholar][Crossref]
  102. Wiegratz I, Kuhl H. Long-cycle treatment with oral contraceptives. Drugs 2004;64:2447-62. [Google Scholar][Crossref]
  103. Wong CS, Lim GH, Gao F, Jakes RW, Offman J, Chia KS, et al. Mammographic density and its interaction with other breast cancer risk factors in an Asian population. Br J Cancer 2011;104(5):871-4. [Google Scholar][Crossref]
  104. Wu L, Janagam DR, Mandrell TD, Johnson JR, Lowe TL. Long-acting injectable hormonal dosage forms for contraception. Pharm Res 2015;32:2180-91. [Google Scholar][Crossref]
  105. Yaghjyan L, Mahoney MC, Succop P, Wones R, Buckholz J, Pinney S. Relationship between breast cancer risk factors and mammographic breast density in the Fernald Community Cohort. Br J Cancer 2012;106(5):996-1003. [Google Scholar][Crossref]
  106. Yaghjyan L, Smotherman C, Heine J, Colditz GA, Rosner B, Tamimi RM. Associations of oral contraceptives with mammographic breast density in premenopausal women. Cancer Epidemiol Biomarkers Prev 2022;31(2):436-42. [Google Scholar][Crossref]
  107. Yang G, Nowsheen S, Aziz K, Georgakilas AG. Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs. Pharmacol Ther 2013;139(3):392-404. [Google Scholar][Crossref]

How to Cite

OPIA, F. N., MATTHEW, K. A., & MATTHEW, T. F. (2022). Leveraging Algorithmic and Machine Learning Technologies for Breast Cancer Management in Sub-Saharan Africa. International Journal of Medical and All Body Health Research, 3(4), 107-121. https://doi.org/10.54660/IJMBHR.2022.3.1.48-62

OPIA, Frank Nwaogelenya, et al. "Leveraging Algorithmic and Machine Learning Technologies for Breast Cancer Management in Sub-Saharan Africa." International Journal of Medical and All Body Health Research, vol. 3, no. 4, 2022, pp. 107-121. https://doi.org/10.54660/IJMBHR.2022.3.1.48-62.

OPIA, F. N., MATTHEW, K. A. and MATTHEW, T. F. (2022) 'Leveraging Algorithmic and Machine Learning Technologies for Breast Cancer Management in Sub-Saharan Africa', International Journal of Medical and All Body Health Research, 3(4), pp. 107-121. doi: 10.54660/IJMBHR.2022.3.1.48-62.

OPIA FN, MATTHEW KA, MATTHEW TF. Leveraging Algorithmic and Machine Learning Technologies for Breast Cancer Management in Sub-Saharan Africa. International Journal of Medical and All Body Health Research. 2022;3(4):107-121. doi:10.54660/IJMBHR.2022.3.1.48-62

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