International Journal of Medical and All Body Health Research  |  e-ISSN: 2582-8940  |  Double-Blind Peer Review  |  Open Access  |  CC BY-NC-SA 4.0

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     2026:7/4

International Journal of Medical and All Body Health Research

e-ISSN: 2582-8940 | Open Access

Oral Infection by Lichen Planus: Types, Relevance, and Significance: A Review 

Enas Abdul Munieem Al-Layla, Enas Yaseen Shahab, Basima A Abdullah, Anmar Ahmed Al Taie

Department of Biology, College of Science, University of Mosul, Iraq; Department of Dental Basic Sciences, College of Dentistry, University of Mosul, Iraq

Article Information

Volume / Issue5 / 3 (July-September 2024)
Pages47-54
AccessOpen Access

Publication Timeline

  • Received25 June 2024
  • Accepted03 July 2024

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Abstract

Lichen planus is a chronic inflammatory condition that affects the skin. It is referred to as oral lichen planus (OLP) when it develops inside the mouth. The condition may only occur in the mouth or also affect other body parts at the same time. It can also occur in the genitals, nails, and scalp. The condition is marked by the onset of a non-infectious, itchy rash. The rash is often small with an irregular shape. It also has a flat top and appears as pink or purple bumps. OLP affects about 1% of the population. OLP is sometimes triggered by the body's reaction to metals placed in the mouth. Examples are dental fillings and metal braces. There have also been reports of the disorder occurring due to mouth mannerisms. Examples are biting the cheeks or tongue. Clinically, six types of OLP, namely reticular, popular, plaque-like, atrophic/erosive, ulcerative, and bullous types, can be identified. OLP more commonly affects the buccal mucosa, tongue, and gingiva. It is important to note that OLP is not an infection. It is also not contagious. It is not passed on from person to person. It is also not linked to nutrition or nutritional deficiency. However, eating certain fruits, tomato-based products, and spicy food has been found to make the symptoms worse.

Keywords

Lichen planusType of OLPDiagnosis of OLP

References

  1. Jana A, Thomas J, Ghosh P. Erosive oral lichen planus inflicts higher cellular stress than the reticular type. Journal of Oral and Maxillofacial Pathology. 2021;25(2):279-285. Available from: https://lww.com [Google Scholar][Crossref]
  2. Abe A, Ito Y, Hayashi H, Momokita M, Taniguchi S, Nakayama A. Evaluation of the classification and clinical characteristics of oral lichen planus and its treatment effect in different clinical types: a retrospective study. Advances in Oral and Maxillofacial Surgery. 2022;8:100369. Available from: https://sciencedirect.com [Google Scholar][Crossref]
  3. Vičić M, Hlača N, Kaštelan M, Brajac I, Sotošek V, Prpić Massari L. Comprehensive insight into lichen planus immunopathogenesis. International Journal of Molecular Sciences. 2023;24(3):3038. Available from: https://mdpi.com [Google Scholar][Crossref]
  4. Louisy A, Humbert E, Samimi M. Oral lichen planus: an update on diagnosis and management. American Journal of Clinical Dermatology. 2024;25(1):35-53. [HTML] [Google Scholar][Crossref]
  5. González-Moles MÁ, Warnakulasuriya S, González-Ruiz I, Ayén Á, González-Ruiz L, Ruiz-Ávila I, Ramos-García P. Dysplasia in oral lichen planus: relevance, controversies and challenges. A position paper. Medicina Oral, Patología Oral y Cirugía Bucal. 2021;26(4). Available from: https://nih.gov [Google Scholar][Crossref]
  6. Liu W, Ma L, Song C, Li C, Shen Z, Shi L. Research trends and characteristics of oral lichen planus: A bibliometric study of the top-100 cited articles. Medicine. 2020;99(18) [Google Scholar][Crossref]
  7. . Available from: https://lww.com [Google Scholar][Crossref]
  8. De D, Jain S, Dev A, Chatterjee D. Oral lichen planus‐ like lesions in the skin of color: a review. International Journal of Dermatology. 2024. [HTML] [Google Scholar][Crossref]
  9. Osipowicz K, Turkowski P, Zdolińska-Malinowska I. Predictive Model Based on Artificial Neural Network Validated by Histopathology and Direct Immunofluorescence for the Diagnosis of Oral Lichen Planus. Diagnostics. 2024;14(1). Available from: https://nih.gov [Google Scholar][Crossref]
  10. Ghazi N, Khorasanchi M. Markers associated with malignant transformation of oral lichen planus: A review article. Archives of Oral Biology. 2021;123. [HTML] [Google Scholar][Crossref]
  11. Idrees M, Kujan O, Shearston K, Farah CS. Oral lichen planus has a very low malignant transformation rate: A systematic review and meta‐analysis using strict diagnostic and inclusion criteria. Journal of Oral Pathology & Medicine. 2021;50(3):287-298. Available from: https://uwa.edu.au [Google Scholar][Crossref]
  12. Pranckutė R. Web of Science (WoS) and Scopus: The titans of bibliographic information in today's academic world. Publications. 2021. Available from: https://mdpi.com [Google Scholar][Crossref]
  13. Singh VK, Singh P, Karmakar M, Leta J, Mayr P. The journal coverage of Web of Science, Scopus, and Dimensions: A comparative analysis. Scientometrics. 2021. Available from: https://researchgate.net [Google Scholar][Crossref]
  14. Sree SS, Vadivel JK. Prevalence of Reticular Oral Lichen Planus: A Retrospective Study. Indian Journal of Forensic Medicine & Toxicology. 2020;14(4). [HTML] [Google Scholar][Crossref]
  15. Osipoff A, Carpenter MD, Noll JL, Valdez JA, Gormsen M, Brennan MT. Predictors of symptomatic oral lichen planus. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2020;129(5):468-477. [HTML] [Google Scholar][Crossref]
  16. Jurczyszyn K, Trzeciakowski W, Kozakiewicz M, Kida D, Malec K, Karolewicz B, et al. Fractal dimension and texture analysis of lesion autofluorescence in the evaluation of oral lichen planus treatment effectiveness. Materials. 2021;14(18):5448. Available from: https://mdpi.com [Google Scholar][Crossref]
  17. Zborowski J, Kida D, Szarwaryn A, Nartowski K, Rak P, Jurczyszyn K, et al. A comparison of clinical efficiency of photodynamic therapy and topical corticosteroid in the treatment of oral lichen planus: a split-mouth randomized controlled study. Journal of Clinical Medicine. 2021;10(16):3673. Available from: https://mdpi.com [Google Scholar][Crossref]
  18. Khabibova NN. Examination of patients with different forms of RFL MMOC Sobirov Sh. [HTML] [Google Scholar][Crossref]
  19. Halonen P. Lichen sclerosus and lichen planus in women: Incidence, risk of cancer, and causes of death [dissertation]. Helsinki: University of Helsinki; 2020. [Google Scholar][Crossref]
  20. Tarquinio SBC, Peres MA, de Oliveira LJC, da Silva KD. Oral lesions in soft tissues. In: Oral Epidemiology: A Textbook on Oral Health Conditions, Research Topics and Methods. 2021. p. 251-263. [HTML] [Google Scholar][Crossref]
  21. Sartori AJ, Dewes R, Madazio G, Moreti F, Behlau M. Vocal deviation in individuals with suggestive signs and symptoms of laryngopharyngeal reflux. CoDAS. 2022. Available from: https://scielo.br [Google Scholar][Crossref]
  22. Wu Y, Zhang Y, Li C, Xie Y, Jiang S, Jiang Y, et al. Follicular lymphoma manifests as multiple erosive and proliferative lesions of the oral mucosa: case report and brief literature review. BMC Oral Health . 2022;22(1):514. Available from: https://springer.com [Google Scholar][Crossref]
  23. Iles R, Simms M, Ledsam A. Oral mucosal manifestations of systemic disease. InnovAiT. 2021. [HTML] [Google Scholar][Crossref]
  24. Reiser C, Girschick H. When the skin turns blue, it bleeds, and then turns black. Clinical Examples in Pediatric Rheumatology. 2024. [HTML] [Google Scholar][Crossref]
  25. Mirfarsi S, Seleem D, Sathananthan A. A patient with Addison disease (primary adrenal insufficiency) presenting for surgical extraction of third molars. Clinical Decisions in Medically Complex Dental Patients, Part II, An Issue of Dental Clinics of North America. 2023;67(4):585. [HTML] [Google Scholar][Crossref]
  26. González‐Moles M, Ramos‐García P. Oral lichen planus and related lesions: What should we accept based on the International Journal of Medical and All Body Health Research www.allmedicaljournal.com available evidence? Oral Diseases. 2023. Available from: https://wiley.com [Google Scholar][Crossref]
  27. Gururaj N, Hasinidevi P, Janani V, Divynadaniel T. Diagnosis and management of oral lichen planus– Review. Journal of Oral and Maxillofacial Pathology. 2021;25(3):383-393. Available from: https://lww.com [Google Scholar][Crossref]
  28. Sciuca AM, Toader MP, Stelea CG, Maftei GA, Ciurcanu OE, Stefanescu OM, et al. Desquamative gingivitis in the context of autoimmune bullous dermatoses and lichen planus—Challenges in the diagnosis and treatment. Diagnostics. 2022;12(7):1754. Available from: https://mdpi.com [Google Scholar][Crossref]
  29. Radochová V, Koberová Ivančaková R, Heneberk O, Slezák R. The characteristics of patients with oral lichen planus and malignant transformation—A retrospective study of 271 patients. International Journal of Environmental Research and Public Health . 2021;18(12):6525. Available from: https://mdpi.com [Google Scholar][Crossref]
  30. González‐Moles MÁ, Warnakulasuriya S, González‐ Ruiz I, González‐Ruiz L, Ayén Á, Lenouvel D, et al. Worldwide prevalence of oral lichen planus: A systematic review and meta‐analysis. Oral Diseases. 2021;27(4):813-828. [HTML] [Google Scholar][Crossref]
  31. Elenbaas A, Enciso R, Al-Eryani K. Oral lichen planus: a review of clinical features, etiologies, and treatments. Dentistry Review; c2022. Available from: https://sciencedirect.com [Google Scholar][Crossref]
  32. Li C, Tang X, Zheng X, Ge S, Wen H, Lin X, et al. Global prevalence and incidence estimates of oral lichen planus: a systematic review and meta-analysis. JAMA Dermatology. 2020;156(2):172-181. Available from: https://jamanetwork.com [Google Scholar][Crossref]
  33. Radwan-Oczko M, Sokół I, Babuśka K, Owczarek-Drabińska JE. Prevalence and characteristic of oral mucosa lesions. Symmetry. 2022;14(2):307. Available from: https://mdpi.com [Google Scholar][Crossref]
  34. Ricci M, Lanza S, Scardina GA, Messina P. Prevalence and characteristics of oral lichen planus: A retrospective study of 93 patients. Minerva Stomatologica. 2021;70(2):96-101. Available from: https://sciencedirect.com [Google Scholar][Crossref]
  35. Corso CD, Park HS, Chen RC. Erectile dysfunction and the risks and benefits of radical prostatectomy, external beam radiation therapy, and brachytherapy in younger men: A comprehensive review. Oncology Reviews. 2020;14(4):471. Available from: https://nih.gov [Google Scholar][Crossref]
  36. Sikder P, Mukherjee S, Ganguly P, Maulik N, Das A. Vitamin D and its correlation with autoimmune disease: An insight. Journal of Steroid Biochemistry and Molecular Biology. 2023;231:106085. Available from: https://sciencedirect.com [Google Scholar][Crossref]
  37. Della Vella F, Lauritano D, Pannone G, Del Prete R, Di Stasio D, Contaldo M, Petruzzi M. Prevalence of HPV in patients affected by oral lichen planus: a prospective study using two different chair‐side sampling methods. Journal of Oral Pathology & Medicine. 2021;50(7):716-722. [HTML] [Google Scholar][Crossref]
  38. Manfredini M, Pedroni G, Bigi L, Apponi R, Dello Diago AM, Dattola A, et al. Acquired white oral lesions with specific patterns: oral lichen planus and lupus erythematosus. Dermatology Practical & Conceptual. 2021;11(3). Available from: https://nih.gov [Google Scholar][Crossref]
  39. Lucchese A, Di Stasio D, Romano A, Fiori F, De Felice GP, Lajolo C, et al. Correlation between oral lichen planus and viral infections other than HCV: a systematic review. Journal of Clinical Medicine. 2022;11(18):5487. Available from: https://mdpi.com [Google Scholar][Crossref]
  40. Scelza G, Amato A, Pagano AM, De Matteis G, Caruso R, Scelza A, et al. Effect of hepatitis C antiviral therapy on oral lichen planus and hyposalivation in inmates. Annals of Gastroenterology. 2022;35(1):74. Available from: https://nih.gov [Google Scholar][Crossref]
  41. Pitak-Arnnop P, Subbalekha K, Sirintawat N, Tangmanee C, Auychai P, Muangchan C, et al. Are oral lichen planus patients at high risk of hepatitis C? A case-control study. Journal of Stomatology, Oral and Maxillofacial Surgery. 2022;123(3). Available from: https://researchgate.net [Google Scholar][Crossref]
  42. Roberts SL, Bhamra R, Ilankovan V. The malignant transformation rate of erosive oral lichen planus—a retrospective study. British Journal of Oral and Maxillofacial Surgery. 2024. [HTML] [Google Scholar][Crossref]
  43. Modak B, Kulkarni S. Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity—a literature review. Oral Oncology Reports; c2024. Available from: https://sciencedirect.com [Google Scholar][Crossref]
  44. Jenkins TM, Mills AM. Putative precancerous lesions of vulvar squamous cell carcinoma. Seminars in Diagnostic Pathology. 2021. [HTML] [Google Scholar][Crossref]
  45. Mustafa E, Parmar S, Praveen P. Premalignant lesions and conditions of the oral cavity. In: Oral and Maxillofacial Surgery for the Clinician. Springer. c2021. p. 1845-1852. Available from: https://springer.com Copyright and License © The Author(s). Authors retain the copyright of their published articles. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution Non Commercial-Share A like 4.0 International (CC BY-NC-SA 4.0) License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. [Google Scholar][Crossref]

How to Cite

Al-Layla, E. A. M., Shahab, E. Y., Abdullah, B. A., & Taie, A. A. A. (2024). Oral Infection by Lichen Planus: Types, Relevance, and Significance: A Review . International Journal of Medical and All Body Health Research, 5(3), 47-54. https://doi.org/10.54660/IJMBHR.2024.5.3.47-54

Al-Layla, Enas Abdul Munieem, et al. "Oral Infection by Lichen Planus: Types, Relevance, and Significance: A Review ." International Journal of Medical and All Body Health Research, vol. 5, no. 3, 2024, pp. 47-54. https://doi.org/10.54660/IJMBHR.2024.5.3.47-54.

Al-Layla, E. A. M., Shahab, E. Y., Abdullah, B. A. and Taie, A. A. A. (2024) 'Oral Infection by Lichen Planus: Types, Relevance, and Significance: A Review ', International Journal of Medical and All Body Health Research, 5(3), pp. 47-54. doi: 10.54660/IJMBHR.2024.5.3.47-54.

Al-Layla EAM, Shahab EY, Abdullah BA, Taie AAA. Oral Infection by Lichen Planus: Types, Relevance, and Significance: A Review . International Journal of Medical and All Body Health Research. 2024;5(3):47-54. doi:10.54660/IJMBHR.2024.5.3.47-54

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