In view of pregnancy possessing the properties of mild however considerable significant inflammatory action under physiological circumstances, ongetting complicated byobesity the chances of a continuous inflammatory state enhances with subsequent numerous consequences with additional complications correlated with acute inflammation. Regarding this the part of resolvins alias Specialized proresolving mediators (SPM) obtained from Omega3 essentiafatty acids might bekey. Actually differential generation of multiple high risk situations is correlated with child birth along with neonatal health, the association amongst, maternal omega 3 fatty acids consumption as well as resolvins amounts in maternal blood along with placental level in addition to greater amounts observed in breast milk at the time of first mth of breast feeding, represent certain of the maximum significant cornerstone concerning these autacoids. In addition to that escalation of scientific corroboration proves the absence of SPM at the immuno metabolic tissue level regarding obesity. Moreover, the obesity correlated absence of SPMs apparently is the deciding factor even regarding the recent Coronavirus disease (COVID19) pandemic since apparently it is amongst the reasons correlated with greater complications in addition to the negative results of SARS-CoV2 infection. The utilization of metabolomics in this speciality has been clarified, with the information that via metabolome it is feasible to watch the multiple along with complicated crosstalk amongst mother, placenta along with fetus, regarding the Identification of particular biomarker regarding the anticipation, diagnosis besides supervision of different obstetric situations. Nevertheless, greater evaluation is required for part of resolving as biomarkers of Maternal –Fetal outcomes besides generation of enough values regarding integration in pregnant women with Omega3 fatty acids or with greater derivatives for ensuring ideal SPM generation under high risk situations.