Sexual dysfunction is a common malady. It causes immense emotional suffering and interferes with social wellbeing. Many physical and psychological ailments are frequently implicated in its development and progression. There are several therapeutic options available for its attenuation. However, more recently, the focus has shifted significantly to several lifestyle factors that can help in its prevention. A brief review of these influences exerted by the five major lifestyles, namely, smoking, obesity, exercise, alcohol intake, and diet is done in this manuscript.