Background: A crucial defense against the coronavirus disease 19 (COVID-19) pandemic is vaccination. It's crucial to look into students' opinions toward the COVID-19 vaccine in order to administer vaccination and immunization programs successfully. To determine the opinions of students at Mosul University about the COVID-19 vaccine. Materials and Methods: The attitudes of university students in Mosul, Iraq, were examined using a descriptive research methodology. The project started in September and will be finished in December 2023. Only 938 individuals, including 402 men and 536 women. Three sections made up the questionnaire: The first part of the survey asked about the respondents' information source for learning about the COVID-19 vaccination; the second part asked about their profile (age, gender, type of college attended, and place of residence); and the final part asked about their opinions of COVID-19 vaccines. Results: The study found that 57.15% of the questionnaire respondents were female students. The average age of the participants was between 21 and 23, which was 48.52%. 85.07% of the study's participants were university students from urban locations, and the majority of participants were from humanitarian institutions. Conclusion: According to the findings of this study, college students in Mosul had a positive attitude toward receiving corona virus vaccinations.