Acne vulgaris is a chronic disorder of the pilosebaceous unit that causes non-inflammatory lesions (open and closed comedones), inflammatory lesions (papules, pustules, and nodules), and varying degrees of scarring. Homoeopathic medicines, when prescribed after individualization, can play significant role in achieving cure. A 22-year-old female patient attended outpatient department (OPD) chiefly for the complaints of red, pustular and painful eruptions on the face. She had been on conventional treatment for some time without satisfactory relief, so patient turned to homoeopathic treatment. After detailed case taking and repertorisation, Natrum muriaticum 30C was prescribed. Within three months of homoeopathic treatment, the patient showed marked improvement; only residual scars remained, with no recurrence of new eruptions observed during subsequent follow-ups. This case highlights the potential of Individualized Homoeopathic Treatment in the successful management of Acne vulgaris.