<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "https://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article" dtd-version="1.2" xml:lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">IJMABHR</journal-id>
<journal-title-group><journal-title>International Journal of Medical and All Body Health Research</journal-title><abbrev-journal-title>IJMABHR</abbrev-journal-title></journal-title-group>
<issn pub-type="epub">2582-8940</issn>
<publisher><publisher-name>Anfo Publication House</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">386</article-id>
<article-id pub-id-type="doi">10.54660/IJMBHR.2025.6.3.217-221</article-id>
<title-group><article-title>Evaluation of Tear Film Dysfunction and Dry Eye Disease after Uncomplicated Cataract Surgery</article-title></title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><name><surname>Bansal</surname><given-names>Swati</given-names></name><xref ref-type="aff" rid="aff1"/></contrib>
<contrib contrib-type="author"><name><surname>Suman</surname><given-names>Nupur</given-names></name><xref ref-type="aff" rid="aff2"/></contrib>
<contrib contrib-type="author"><name><surname>Chaturvedi</surname><given-names>Pushpalata</given-names></name><xref ref-type="aff" rid="aff3"/></contrib>
<contrib contrib-type="author"><name><surname>Saxena</surname><given-names>Ruchi</given-names></name><xref ref-type="aff" rid="aff4"/></contrib>
<contrib contrib-type="author"><name><surname>Jyostna</surname></name><xref ref-type="aff" rid="aff4"/></contrib>
<contrib contrib-type="author"><name><surname>Singh</surname><given-names>Priya</given-names></name><xref ref-type="aff" rid="aff1"/></contrib>
<aff id="aff1"><label>1</label>Department of Ophthalmology, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India</aff>
<aff id="aff2"><label>2</label>Head of Department, Department of Ophthalmology, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India</aff>
<aff id="aff3"><label>3</label>Associate Professor, Department of Ophthalmology, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India</aff>
<aff id="aff4"><label>4</label>Assistant Professor, Department of Ophthalmology, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India</aff>
</contrib-group>
<pub-date publication-format="electronic" date-type="pub"><day>16</day><month>08</month><year>2025</year></pub-date>
<volume>6</volume>
<issue>3</issue>
<fpage>217</fpage>
<lpage>221</lpage>
<history>
<date date-type="received"><day>04</day><month>07</month><year>2025</year></date>
<date date-type="accepted"><day>03</day><month>08</month><year>2025</year></date>
</history>
<permissions><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by-nc-sa/4.0/?utm"><license-p>CC BY-NC-SA 4.0</license-p></license></permissions>
<self-uri xlink:href="https://www.allmedicaljournal.com/article/386/evaluation-of-tear-film-dysfunction-and-dry-eye-disease-after-uncomplicated-cataract-surgery"/>
<self-uri content-type="pdf" xlink:href="https://www.allmedicaljournal.com/article/386/download"/>
<abstract><p>Dry eye disease (DED) represents one of the most common complications following cataract surgery, significantly impacting patient quality of life and visual outcomes. This prospective study evaluated tear film dysfunction and dry eye symptoms in 180 patients who underwent uncomplicated phacoemulsification with intraocular lens implantation over a 12-month follow-up period. Patients were assessed using comprehensive tear film evaluation including Schirmer&apos;s test, tear break-up time (TBUT), ocular surface disease index (OSDI), and fluorescein staining at baseline, 1 week, 1 month, 3 months, 6 months, and 12 months post-operatively. Results demonstrated a significant increase in dry eye symptoms and tear film instability during the first 3 months post-surgery, with 67.2% of patients developing new-onset dry eye or experiencing worsening of pre-existing symptoms. The mean OSDI score increased from 18.4±12.3 pre-operatively to 42.7±18.9 at 1 month (p</p></abstract>
<kwd-group kwd-group-type="author"><kwd>Dry Eye Disease</kwd><kwd>Cataract Surgery</kwd><kwd>Tear Film Dysfunction</kwd><kwd>Ocular Surface Disease Index</kwd><kwd>Tear Break-Up Time</kwd><kwd>Post-Operative Complications</kwd></kwd-group>
</article-meta>
</front>
<back><ref-list><title>References</title>
<ref id="R1"><label>1</label><mixed-citation>Liu YC, Wilkins M, Kim T, et al. Cataracts. Lancet. 2017;390(10094):600-612.</mixed-citation></ref>
<ref id="R2"><label>2</label><mixed-citation>Epitropoulos AT, Matossian C, Berdy GJ, et al. Effect of tear osmolarity on repeatability of keratometry for cataract surgery planning. J Cataract Refract Surg. 2015;41(8):1672-1677.</mixed-citation></ref>
<ref id="R3"><label>3</label><mixed-citation>Kasetsuwan N, Satitpitakul V, Changul T, et al. Incidence and pattern of dry eye after cataract surgery. PLoS One. 2013;8(11):e78657.</mixed-citation></ref>
<ref id="R4"><label>4</label><mixed-citation>Cho YK, Kim MS. Dry eye after cataract surgery and associated intraoperative risk factors. Korean J Ophthalmol. 2009;23(2):65-73.</mixed-citation></ref>
<ref id="R5"><label>5</label><mixed-citation>Sutu C, Fukuoka H, Afshari NA. Mechanisms and management of dry eye in cataract surgery patients. Curr Opin Ophthalmol. 2016;27(1):24-30.</mixed-citation></ref>
<ref id="R6"><label>6</label><mixed-citation>Mencucci R, Favuzza E, Decandia G, et al. Effect of a hyaluronic acid and carboxymethylcellulose ophthalmic solution on ocular comfort and tear-film instability after cataract surgery. J Cataract Refract Surg. 2015;41(8):1699-1704.</mixed-citation></ref>
<ref id="R7"><label>7</label><mixed-citation>Zhai L, Zhao M. The application of hyaluronic acid in corneal diseases. Int Ophthalmol. 2019;39(10):2291-2301.</mixed-citation></ref>
<ref id="R8"><label>8</label><mixed-citation>Khanal S, Tomlinson A, Esakowitz L, et al. Changes in corneal sensitivity and tear physiology after phacoemulsification. Ophthalmic Physiol Opt. International Journal of Medical and All Body Health Research www.allmedicaljournal.com 2008;28(2):127-134.</mixed-citation></ref>
<ref id="R9"><label>9</label><mixed-citation>Trattler WB, Majmudar PA, Donnenfeld ED, et al. The Prospective Health Assessment of Cataract Patients&apos; Ocular Surface (PHACO) study: the effect of dry eye. Clin Ophthalmol. 2017;11:1423-1430.</mixed-citation></ref>
<ref id="R10"><label>10</label><mixed-citation>Starr CE, Gupta PK, Farid M, et al. An algorithm for the preoperative diagnosis and treatment of ocular surface disorders. J Cataract Refract Surg. 2019;45(5):669-684.</mixed-citation></ref>
<ref id="R11"><label>11</label><mixed-citation>Yu J, Asche CV, Fairchild CJ. The economic burden of dry eye disease in the United States: a decision tree analysis. Cornea. 2011;30(4):379-387.</mixed-citation></ref>
<ref id="R12"><label>12</label><mixed-citation>Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017;15(3):276-283.</mixed-citation></ref>
<ref id="R13"><label>13</label><mixed-citation>Schiffman RM, Christianson MD, Jacobsen G, et al. Reliability and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118(5):615-621.</mixed-citation></ref>
<ref id="R14"><label>14</label><mixed-citation>Miller KL, Walt JG, Mink DR, et al. Minimal clinically important difference for the ocular surface disease index. Arch Ophthalmol. 2010;128(1):94-101.</mixed-citation></ref>
<ref id="R15"><label>15</label><mixed-citation>Wolffsohn JS, Arita R, Chalmers R, et al. TFOS DEWS II Diagnostic Methodology report. Ocul Surf. 2017;15(3):539-574.</mixed-citation></ref>
<ref id="R16"><label>16</label><mixed-citation>Whitcher JP, Shiboski CH, Shiboski SC, et al. A simplified quantitative method for assessing keratoconjunctivitis sicca from the Sjögren&apos;s Syndrome International Registry. Am J Ophthalmol. 2010;149(3):405-415.</mixed-citation></ref>
<ref id="R17"><label>17</label><mixed-citation>Bron AJ, Evans VE, Smith JA. Grading of corneal and conjunctival staining in the context of other dry eye tests. Cornea. 2003;22(7):640-650.</mixed-citation></ref>
<ref id="R18"><label>18</label><mixed-citation>Li XM, Hu L, Hu J, et al. Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery. Cornea. 2007;26(9 Suppl 1):S16-20.</mixed-citation></ref>
<ref id="R19"><label>19</label><mixed-citation>Amparo F, Hamrah P, Schaumberg DA, et al. The ocular surface following cataract surgery. Curr Opin Ophthalmol. 2015;26(4):353-358.</mixed-citation></ref>
<ref id="R20"><label>20</label><mixed-citation>Woodward MA, Randleman JB, Stulting RD. Dissatisfaction after multifocal intraocular lens implantation. J Cataract Refract Surg. 2009;35(6):992-997.</mixed-citation></ref>
<ref id="R21"><label>21</label><mixed-citation>Ishrat S, Nema N, Chandravanshi SC. Incidence and pattern of dry eye after phacoemulsification. Indian J Ophthalmol. 2019;67(7):1065-1069.</mixed-citation></ref>
<ref id="R22"><label>22</label><mixed-citation>Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334-365.</mixed-citation></ref>
<ref id="R23"><label>23</label><mixed-citation>Nelson JD, Shimazaki J, Benitez-del-Castillo JM, et al. The international workshop on meibomian gland dysfunction: report of the definition and classification subcommittee. Invest Ophthalmol Vis Sci. 2011;52(4):1930-1937.</mixed-citation></ref>
</ref-list></back>
</article>