IJMABHR International Journal of Medical and All Body Health ResearchIJMABHR 2582-8940 Anfo Publication House 383 10.54660/IJMBHR.2025.6.3.193-199 Comparative Study for Efficacy of Ultrasound Guided Pectoral Nerve Block versus Erector Spinae Plane Block for Post Operative Analgesia in Modified Radical Mastectomy KumarVadla Vinay SharmaShailja JagarKeshav Dev BhardwajAbhishek SehgalAnkur KumariJayshree Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India Professor and HOD Anaesthesia, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India Associate Professor, HOD, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India Assistant Professor, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India Post Graduate Resident, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 27072025 6 3 193 199 16062025 19072025 CC BY-NC-SA 4.0

Modified Radical Mastectomy (MRM) is associated with significant postoperative pain. Regional anesthesia techniques like Pectoral Nerve Block (PECS) and Erector Spinae Plane Block (ESPB) have emerged as effective analgesic modalities. This study compares the efficacy of ultrasound-guided PECS block versus ESPB for postoperative analgesia in MRM patients. This prospective, randomized, double-blind study included 120 patients undergoing MRM, divided into two groups (n=60 each). Group P received PECS II block with 30ml of 0.25% bupivacaine, while Group E received ESPB at T4 level with the same dose. Primary outcome was 24-hour postoperative morphine consumption. Secondary outcomes included Visual Analog Scale (VAS) scores, time to first rescue analgesia, patient satisfaction, and complications. Mean 24-hour morphine consumption was significantly lower in Group P (8.4±2.3mg) compared to Group E (12.6±3.1mg) (p

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