<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2 20190208//EN" "https://jats.nlm.nih.gov/publishing/1.2/JATS-journalpublishing1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" article-type="research-article" dtd-version="1.2" xml:lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">IJMABHR</journal-id>
<journal-title-group><journal-title>International Journal of Medical and All Body Health Research</journal-title><abbrev-journal-title>IJMABHR</abbrev-journal-title></journal-title-group>
<issn pub-type="epub">2582-8940</issn>
<publisher><publisher-name>Anfo Publication House</publisher-name></publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">379</article-id>
<article-id pub-id-type="doi">10.54660/IJMBHR.2025.6.3.161-170</article-id>
<title-group><article-title>A Study to Compare and Evaluate the Analgesic Efficacy of Erector Spinae Block and Anterior Quadratus Lumborum Block Using Levobupivacaine in Renal Surgeries</article-title></title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes"><name><surname>Kumari</surname><given-names>Jayshree</given-names></name><xref ref-type="aff" rid="aff1"/></contrib>
<contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Shailja</given-names></name><xref ref-type="aff" rid="aff2"/></contrib>
<contrib contrib-type="author"><name><surname>Bhardwaj</surname><given-names>Abhishek</given-names></name><xref ref-type="aff" rid="aff3"/></contrib>
<contrib contrib-type="author"><name><surname>Khushboo</surname></name><xref ref-type="aff" rid="aff4"/></contrib>
<contrib contrib-type="author"><name><surname>Tanwar</surname><given-names>Mohit</given-names></name><xref ref-type="aff" rid="aff4"/></contrib>
<aff id="aff1"><label>1</label>Post Graduate Resident, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India</aff>
<aff id="aff2"><label>2</label>Professor and HOD, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India</aff>
<aff id="aff3"><label>3</label>Assistant Professor, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India</aff>
<aff id="aff4"><label>4</label>PG Resident, Department of Anaesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India</aff>
</contrib-group>
<pub-date publication-format="electronic" date-type="pub"><day>16</day><month>07</month><year>2025</year></pub-date>
<volume>6</volume>
<issue>3</issue>
<fpage>161</fpage>
<lpage>170</lpage>
<history>
<date date-type="received"><day>03</day><month>06</month><year>2025</year></date>
<date date-type="accepted"><day>04</day><month>07</month><year>2025</year></date>
</history>
<permissions><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by-nc-sa/4.0/?utm"><license-p>CC BY-NC-SA 4.0</license-p></license></permissions>
<self-uri xlink:href="https://www.allmedicaljournal.com/article/379/a-study-to-compare-and-evaluate-the-analgesic-efficacy-of-erector-spinae-block-and-anterior"/>
<self-uri content-type="pdf" xlink:href="https://www.allmedicaljournal.com/article/379/download"/>
<abstract><p>Background: Regional anesthesia techniques have gained prominence in perioperative pain management for renal surgeries. Both erector spinae plane (ESP) block and anterior quadratus lumborum (QLB) block offer promising alternatives for postoperative analgesia.
Objective: To compare and evaluate the analgesic efficacy of ultrasound-guided ESP block versus anterior QLB using levobupivacaine in patients undergoing renal surgeries.
Methods: This prospective, randomized, double-blind study included 80 patients (ASA I-III) scheduled for elective renal surgeries. Patients were randomly allocated into two groups: Group E (ESP block, n=40) and Group Q (anterior QLB, n=40). Both groups received 0.25% levobupivacaine (20ml) under ultrasound guidance. Primary outcomes included postoperative pain scores using Visual Analog Scale (VAS) at rest and movement at 2, 4, 8, 12, and 24 hours. Secondary outcomes included time to first analgesic request, total morphine consumption, patient satisfaction scores, and complications.
Results: Both groups demonstrated significant reduction in postoperative pain scores compared to historical controls. Group E showed statistically significant lower VAS scores at rest at 2 hours (2.1±0.8 vs 2.8±1.1, p=0.002) and 4 hours (2.3±0.9 vs 3.1±1.2, p=0.001) compared to Group Q. Time to first analgesic request was longer in Group E (8.2±2.1 hours) versus Group Q (6.4±1.8 hours, p=0.001). Total 24-hour morphine consumption was significantly lower in Group E (12.4±3.2mg) compared to Group Q (16.8±4.1mg, p</p></abstract>
<kwd-group kwd-group-type="author"><kwd>Erector Spinae Plane Block</kwd><kwd>Quadratus Lumborum Block</kwd><kwd>Levobupivacaine</kwd><kwd>Renal Surgery</kwd><kwd>Postoperative Analgesia</kwd><kwd>Regional Anesthesia</kwd></kwd-group>
</article-meta>
</front>
<back><ref-list><title>References</title>
<ref id="R1"><label>1</label><mixed-citation>Grape S, Kirkham KR, Frauenknecht J, Albrecht E. Intra-operative analgesia with remifentanil vs. dexmedetomidine: a systematic review and meta-analysis with trial sequential analysis. Anaesthesia. 2019;74(6):793-800.</mixed-citation></ref>
<ref id="R2"><label>2</label><mixed-citation>Kharasch ED, Brunt LM. Perioperative opioids and public health. Anesthesiology. 2016;124(4):960-5.</mixed-citation></ref>
<ref id="R3"><label>3</label><mixed-citation>Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery: a review. JAMA Surg. 2017;152(3):292-8.</mixed-citation></ref>
<ref id="R4"><label>4</label><mixed-citation>Miller TE, Roche AM, Mythen M. Fluid management and goal-directed therapy as an adjunct to enhanced recovery after surgery (ERAS). Can J Anaesth. 2015;62(2):158-68.</mixed-citation></ref>
<ref id="R5"><label>5</label><mixed-citation>Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The erector spinae plane block: a novel analgesic technique in thoracic neuropathic pain. Reg Anesth Pain Med. 2016;41(5):621-7.</mixed-citation></ref>
<ref id="R6"><label>6</label><mixed-citation>Schwartzmann A, Peng P, Maciel MA, Forero M. Mechanism of the erector spinae plane block: insights from a magnetic resonance imaging study. Can J Anaesth. 2018;65(10):1165-6.</mixed-citation></ref>
<ref id="R7"><label>7</label><mixed-citation>Yang HM, Choi YJ, Kwon HJ, O J, Cho TH, Kim SH. Comparison of injectate spread and nerve involvement between retrolaminar and erector spinae plane blocks in cadavers: a randomized controlled study. Can J Anaesth. 2018;65(10):1224-33.</mixed-citation></ref>
<ref id="R8"><label>8</label><mixed-citation>Blanco R, Ansari T, Girgis E. Quadratus lumborum block for postoperative pain after caesarean section: a randomised controlled trial. Eur J Anaesthesiol. 2015;32(11):812-8.</mixed-citation></ref>
<ref id="R9"><label>9</label><mixed-citation>Blanco R. TAP block under ultrasound guidance: the description of a &quot;no pops&quot; technique. Reg Anesth Pain Med. 2007;32(5):130.</mixed-citation></ref>
<ref id="R10"><label>10</label><mixed-citation>Dam M, Moriggl B, Hansen CK, Hoermann R, Bendtsen TF, Børglum J. The pathway of injectate spread with the transmuscular quadratus lumborum block: a cadaver study. Anesth Analg. 2017;125(1):303-12.</mixed-citation></ref>
<ref id="R11"><label>11</label><mixed-citation>Adhikary SD, El-Boghdadly K, Nasralah Z, Sarwani N, Nixon AM, Chin KJ. A radiologic and anatomic assessment of injectate spread following transmuscular quadratus lumborum block in cadavers. Anaesthesia. 2017;72(1):73-9.</mixed-citation></ref>
<ref id="R12"><label>12</label><mixed-citation>Casati A, Putzu M. Bupivacaine, levobupivacaine and ropivacaine: are they clinically different? Best Pract Res Clin Anaesthesiol. 2005;19(2):247-68.</mixed-citation></ref>
<ref id="R13"><label>13</label><mixed-citation>McLeod GA, Burke D. Levobupivacaine. Anaesthesia. 2001;56(4):331-41.</mixed-citation></ref>
<ref id="R14"><label>14</label><mixed-citation>Brennan TJ. Pathophysiology of postoperative pain. Pain. 2011;152(3 Suppl):S33-40.</mixed-citation></ref>
<ref id="R15"><label>15</label><mixed-citation>Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: risk factors and prevention. Lancet. 2006;367(9522):1618-25.</mixed-citation></ref>
<ref id="R16"><label>16</label><mixed-citation>Ökmen K, Ökmen BM, Topal A. Ultrasound-guided posterior quadratus lumborum block for postoperative pain after laparoscopic cholecystectomy: a randomized controlled double blind study. J Clin Anesth. 2018;49:112-7.</mixed-citation></ref>
<ref id="R17"><label>17</label><mixed-citation>Chin KJ, McDonnell JG, Carvalho B, Sharkey A, Pawa A, Gadsden J. Essentials of our current understanding: abdominal wall blocks. Reg Anesth Pain Med. 2017;42(2):133-83.</mixed-citation></ref>
<ref id="R18"><label>18</label><mixed-citation>Chin KJ, Adhikary S, Sarwani N, Forero M. The analgesic efficacy of pre-operative bilateral erector spinae plane (ESP) blocks in patients having ventral hernia repair. Anaesthesia. 2017;72(4):452-60.</mixed-citation></ref>
<ref id="R19"><label>19</label><mixed-citation>Ueshima H, Otake H, Lin JA. Ultrasound-guided quadratus lumborum block: an updated review of anatomy and techniques. Biomed Res Int. 2017;2017:2752876.</mixed-citation></ref>
<ref id="R20"><label>20</label><mixed-citation>Ivanusic J, Konishi Y, Barrington MJ. A cadaveric study investigating the mechanism of action of erector spinae blockade. Reg Anesth Pain Med. 2018;43(6):567-71.</mixed-citation></ref>
<ref id="R21"><label>21</label><mixed-citation>Adhikary SD, Bernard S, Lopez H, Chin KJ. Erector spinae plane block versus retrolaminar block: a magnetic resonance imaging and anatomical study. Reg Anesth Pain Med. 2018;43(7):756-62.</mixed-citation></ref>
<ref id="R22"><label>22</label><mixed-citation>Aponte A, Sala-Blanch X, Prats-Galino A, Masdeu J, Moreno LA, Sermeus LA. Anatomical evaluation of the extent of spread in the erector spinae plane block: a cadaveric study. Can J Anaesth. 2019;66(8):886-93.</mixed-citation></ref>
<ref id="R23"><label>23</label><mixed-citation>Choi YJ, Kwon HJ, O J, Cho TH, Kim SH, Yang HM. Influence of injectate volume on paravertebral spread in erector spinae plane block: an endoscopic and anatomical evaluation. PLoS One. 2019;14(10):e0224487.</mixed-citation></ref>
<ref id="R24"><label>24</label><mixed-citation>Elsharkawy H, El-Boghdadly K, Barrington M. Quadratus lumborum block: anatomical concepts, mechanisms, and techniques. Anesthesiology. 2019;130(2):322-35.</mixed-citation></ref>
<ref id="R25"><label>25</label><mixed-citation>Carvalho R, Segura E, Loureiro MD, Assunção JP. Quadratus lumborum block in chronic pain after abdominal hernia repair: case report. Rev Bras Anestesiol. 2017;67(1):107-9.</mixed-citation></ref>
<ref id="R26"><label>26</label><mixed-citation>Tulgar S, Kapakli MS, Senturk O, Selvi O, Serifsoy TE, Ozer Z. Evaluation of ultrasound-guided erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: a prospective, randomized, controlled study. J Clin Anesth. 2018;49:101-6.</mixed-citation></ref>
<ref id="R27"><label>27</label><mixed-citation>Nagaraja PS, Ragavendran S, Singh NG, Asai O, Bhavya G, Manjunath N, et al. Comparison of continuous thoracic epidural analgesia with bilateral erector spinae plane block for perioperative pain management in cardiac surgery. Ann Card Anaesth. 2018;21(3):323-7.</mixed-citation></ref>
<ref id="R28"><label>28</label><mixed-citation>Kot P, Rodriguez P, Granell M, Cano B, Rovira L, Morales J, et al. The erector spinae plane block: a narrative review. Korean J Anesthesiol. 2019;72(3):209-International Journal of Medical and All Body Health Research www.allmedicaljournal.com 20.</mixed-citation></ref>
<ref id="R29"><label>29</label><mixed-citation>De Cassai A, Bonvicini D, Correale C, Sandei L, Tulgar S, Tonetti T. Erector spinae plane block: a systematic qualitative review. Minerva Anestesiol. 2019;85(3):308-19.</mixed-citation></ref>
<ref id="R30"><label>30</label><mixed-citation>Lavand&apos;homme P, Steyaert A. Opioid-free anesthesia opioid side effects: tolerance and hyperalgesia. Best Pract Res Clin Anaesthesiol. 2017;31(4):487-98.</mixed-citation></ref>
<ref id="R31"><label>31</label><mixed-citation>Grape S, Tramèr MR. Do we need opioids for postoperative pain management? Best Pract Res Clin Anaesthesiol. 2019;33(3):369-83.</mixed-citation></ref>
<ref id="R32"><label>32</label><mixed-citation>Myles PS, Weitkamp B, Jones K, Melick J, Hensen S. Validity and reliability of a postoperative quality of recovery score: the QoR-40. Br J Anaesth. 2000;84(1):11-5.</mixed-citation></ref>
<ref id="R33"><label>33</label><mixed-citation>Bowyer A, Royse C, Royse A, Hutchison S, van Wijk RM, McCluskey SA. Patient-reported outcome measures and their role in assessing the quality of perioperative care. Anaesthesia. 2014;69(8):801-8.</mixed-citation></ref>
<ref id="R34"><label>34</label><mixed-citation>Pak DJ, Yong RJ, Kaye AD, Urman RD. Chronification of pain: mechanisms, current understanding, and clinical implications. Curr Pain Headache Rep. 2018;22(2):9.</mixed-citation></ref>
<ref id="R35"><label>35</label><mixed-citation>El-Boghdadly K, Pawa A, Chin KJ. Local anesthetic systemic toxicity: current perspectives. Local Reg Anesth. 2018;11:35-44.</mixed-citation></ref>
<ref id="R36"><label>36</label><mixed-citation>Neal JM, Barrington MJ, Fettiplace MR, Gitman M, Memtsoudis SG, Mörwald EE, et al. The Third American Society of Regional Anesthesia and Pain Medicine Practice Advisory on Local Anesthetic Systemic Toxicity: executive summary 2017. Reg Anesth Pain Med. 2018;43(2):113-23.</mixed-citation></ref>
<ref id="R37"><label>37</label><mixed-citation>Sites BD, Taenzer AH, Herrick MD, Gilloon C, Antonakakis J, Richins J, et al. Incidence of local anesthetic systemic toxicity and postoperative neurologic symptoms associated with 12,668 ultrasound-guided nerve blocks: an analysis from a prospective clinical registry. Reg Anesth Pain Med. 2012;37(5):478-82.</mixed-citation></ref>
<ref id="R38"><label>38</label><mixed-citation>Beverly A, Kaye AD, Ljungqvist O, Urman RD. Essential elements of multimodal analgesia in enhanced recovery after surgery (ERAS) guidelines. Anesthesiol Clin. 2017;35(2):e115-43.</mixed-citation></ref>
<ref id="R39"><label>39</label><mixed-citation>Kehlet H, Wilmore DW. Evidence-based surgical care and the evolution of fast-track surgery. Ann Surg. 2008;248(2):189-98.</mixed-citation></ref>
<ref id="R40"><label>40</label><mixed-citation>Marhofer P, Greher M, Kapral S. Ultrasound guidance in regional anaesthesia. Br J Anaesth. 2005;94(1):7-17.</mixed-citation></ref>
<ref id="R41"><label>41</label><mixed-citation>Abrahams MS, Aziz MF, Fu RF, Horn JL. Ultrasound guidance compared with electrical neurostimulation for peripheral nerve block: a systematic review and meta-analysis of randomized controlled trials. Br J Anaesth. 2009;102(3):408-17.</mixed-citation></ref>
<ref id="R42"><label>42</label><mixed-citation>Krediet AC, Moayeri N, van Geffen GJ, Bruhn J, Renes S, Bigeleisen PE, et al. Different approaches to ultrasound-guided thoracic paravertebral block: an illustrated review. Anesthesiology. 2015;123(2):459-74.</mixed-citation></ref>
<ref id="R43"><label>43</label><mixed-citation>Lewis SR, Price A, Walker KJ, McGrattan K, Smith AF. Ultrasound guidance for upper and lower limb blocks. Cochrane Database Syst Rev. 2015;2015(9):CD006459</mixed-citation></ref>
</ref-list></back>
</article>