References

IJMABHR

International Journal of Medical and All Body Health Research

IJMABHR

2582-8940

Anfo Publication House

369

10.54660/IJMBHR.2025.6.3.99-105

Comparative Study of Hyperbaric Ropivacaine 0.75% and Hyperbaric Bupivacaine 0.5% for Spinal Anaesthesia

Jain

Rohit

Goel

Sharad

Sharma

Shailja

Jain

Ankit

1Postgradutae Resident Anaesthesia, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 2Professor Anaesthesia, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 3Hod and Professor Anaesthesia, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 4Md Anaesthesia, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India

01082025

6 3 99 105 23062025 25072025

CC BY-NC-SA 4.0

Background: Local anesthetic selection for spinal anesthesia significantly influences block characteristics, safety profile, and patient outcomes. Ropivacaine, with its reduced cardiotoxicity and neurotoxicity compared to bupivacaine, has emerged as an attractive alternative for neuraxial anesthesia. Objective: To compare the efficacy, safety, and block characteristics of hyperbaric ropivacaine 0.75% versus hyperbaric bupivacaine 0.5% in patients undergoing spinal anesthesia for lower abdominal and lower limb surgeries. Methods: This prospective, randomized, double-blind study included 120 patients (ASA I-II) scheduled for elective surgery under spinal anesthesia. Patients were randomly allocated into two groups: Group R (n=60) received 15 mg of 0.75% hyperbaric ropivacaine, and Group B (n=60) received 15 mg of 0.5% hyperbaric bupivacaine. Primary outcomes included onset and duration of sensory and motor blockade. Secondary outcomes encompassed hemodynamic parameters, recovery characteristics, and adverse effects. Results: Sensory block onset was faster in Group B (4.2±1.1 min) compared to Group R (5.8±1.4 min, p

Spinal AnesthesiaRopivacaineBupivacaineHyperbaric SolutionLocal AnestheticsRegional AnesthesiaNeuraxial Blockade

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