References

IJMABHR

International Journal of Medical and All Body Health Research

IJMABHR

2582-8940

Anfo Publication House

368

10.54660/IJMBHR.2025.6.3.93-98

Comparison of Subcostal Transversus Abdominis Plane Block with Intraperitoneal Instillation of Levobupivacaine 0.25% for Pain Relief After Laparoscopic Cholecystectomy

Bhati

Bobi

Sharma

Shailja

Jagar

Keshav Dev

Sharma

Kajal

Madhrey

Manish

1Postgraduate Resident, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 2HOD & Professor, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 3Associate Professor, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 4Senior Resident MS General Surgery, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India 5Senior Resident, Department of Anesthesia and Critical Care, Saraswathi Institute of Medical Sciences, Pilkhuwa, Hapur, Uttar Pradesh, India

2025

6 3 93 98 18062025 19072025

CC BY-NC-SA 4.0

Background: Laparoscopic cholecystectomy, despite being minimally invasive, is associated with significant postoperative pain that can delay recovery and discharge. This study aimed to compare the efficacy of subcostal transversus abdominis plane (TAP) block with intraperitoneal instillation of levobupivacaine 0.25% for postoperative pain management following laparoscopic cholecystectomy. Methods: A prospective, randomized, double-blind study was conducted on 120 patients undergoing elective laparoscopic cholecystectomy. Patients were randomly allocated into two groups: Group T (n=60) received bilateral subcostal TAP block with 20 mL of 0.25% levobupivacaine on each side, and Group I (n=60) received intraperitoneal instillation of 40 mL of 0.25% levobupivacaine. Primary outcome was postoperative pain scores using Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours. Secondary outcomes included time to first analgesic request, total analgesic consumption, patient satisfaction scores, and adverse effects. Results: Both groups showed significant reduction in postoperative pain compared to historical controls. Group T demonstrated significantly lower VAS scores at 2 hours (3.2±1.1 vs 4.1±1.3, p

Transversus Abdominis Plane BlockIntraperitoneal InstillationLevobupivacaineLaparoscopic CholecystectomyPostoperative AnalgesiaRegional Anesthesia

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