The outbreak of this wide-ranging pandemic has forced the world to identify and produce the therapeutics for the treatment & prevention of it. The Covid-19 is a virulent pneumonia-like disease caused by SARS-COV-2. This pandemic has caused several thousands of deaths. For a few months this pandemic has set pressure on laborites to diagnose this novel virus properly and on the pharmacists, researchers, doctors, scientists, and pharmaceutical companies to develop proper medicine and vaccination against this virus. Proper diagnosis and treatment are essential to treat patients suffering from covid-19. Despite extraordinary advancements in the medical field, presently, there is no effective treatment for this global pandemic. However, fast and rapid research on the epidemiology of SARS-COv-2 is helping in unveiling the potential therapeutic against covid-19.clinical trials and screening for drug development are going on some drugs. Favipiravir, Remdesivir, & dexamethasone have shown promising potential against covid-19. Interferon, tocilizumab, and convalescent plasma therapy have beneficial effects on viral clearance. Trials are going also going on viral S protein targeting vaccines. This review aims to summarize all current therapeutic advancements and vaccinations in the global medicinal system against covid-19.