IJMABHR International Journal of Medical and All Body Health ResearchIJMABHR 2582-8940 Anfo Publication House 218 Effect of intraoperative local Tranexamic acid on length of hospitalization FarshidSaman RezvankhahVahid Nephrology and Kidney Transplant Research Center, Clinical Research Institue, Urmia University of Medical Science, Urmia, Iran 2023 4 4 53 54 10102023 19112023 CC BY-NC-SA 4.0

Background: This study aimed to compare the effect of local intraoperative administration of tranexamic acid on length of stay (LOS) in the hospital. Materials and Methods: The study involved 70 patients undergoing prostatectomy. They received 1 gram of tranexamic acid. The LOS was recorded and the data was analyzed using SPSS version 16. Results: The mean age of the patients was around 70 years. The LOS was not significantly different compared to a group that did not receive tranexamic acid (p=0.058). Conclusion: This study found that the use of tranexamic acid did not result in a significant difference in length of hospital stay.   

 Tranexamic acidslength of stayprostatectomy References Lepor H, Nieder AM, Ferrandino MN. Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases. The Journal of urology. 2001; 166(5):1729-33. Hedican SP, Walsh PC. Postoperative bleeding following radical retropubic prostatectomy. The Journal of urology. 1994; 152(4):1181-3. Catalona WJ, Carvalhal GF, Mager DE, Smith DS. Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies. The Journal of urology. 1999; 162(2):433-8. Djavan B, Agalliu I, Laze J, Sadri H, Kazzazi A, Lepor H. Blood loss during radical prostatectomy: impact on clinical, oncological and functional outcomes and complication rates. BJU international. 2012; 110(1):69-75. Lepor H, Nieder AM, Ferrandino MN. Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases. J Urol. 2001; 166:1729-33. Longo MA, Cavalheiro BT, de Oliveira Filho GR. Systematic review and meta-analyses of tranexamic acid use for bleeding reduction in prostate surgery. Journal of clinical anesthesia. 2018; 48:32-8. Ierardi AM, Jannone ML, Brambillasca PM, Zannoni S, Damiani G, Rossi UG, Granata AM, Petrillo M, Carrafiello G. Bleeding after prostatectomy: endovascular management. Gland Surg. 2019; 8(2):108-114.